Objective: The purpose of this study was to compare maternal and neonatal outcomes of women with gestational hypertension (GHTN), mild chronic hypertension (CHTN), and mild preeclampsia at delivery.
Study Design: A multicenter database that contained 228,668 deliveries was used to extract data on gravid women with GHTN, preeclampsia, and CHTN and on women without hypertensive disease (control group). Univariate and multivariate logistic regression analyses were performed.
Results: There were 4918 women with GHTN, 5274 women with preeclampsia, 2531 women with CHTN, and 15,221 control subjects. Women with GHTN had the greatest risk for blood transfusion (adjusted odds ratio [aOR], 4.6; 95% confidence interval [CI], 3.4-6.3), intensive care unit admission (aOR, 25.7; 95% CI, 9.8-67.3), and lowest risk for stillbirth (aOR, 0.1; 95% CI, 0.04-0.4); women with preeclampsia had the greatest risk for postpartum hypertension (aOR, 9.6; 95% CI, 7.2-12.9). Neonates with GHTN had the greatest risk for ventilator requirements (aOR, 7.5; 95% CI, 4.6-12.4).
Conclusion: Women with gestational hypertension and their neonates had significant risks for morbidity, compared with women with mild chronic hypertension and those with mild preeclampsia.
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http://dx.doi.org/10.1016/j.ajog.2011.06.033 | DOI Listing |
J Clin Psychiatry
January 2025
Department of Psychiatry, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India, Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bangalore, India
Cannabis use during pregnancy is increasing; the study of adverse outcomes in cannabis-exposed pregnancies is therefore important. Previous articles in this series described increased risks of maternal adverse outcomes, fetal adverse outcomes, birth defects in newborns, and autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in childhood. This article examines neuropsychiatric adverse outcomes in offspring gestationally exposed to cannabis.
View Article and Find Full Text PDFCent Eur J Public Health
December 2024
Department of Preclinical Subjects, Faculty of Health Sciences, Palacky University Olomouc, Olomouc, Czech Republic.
Objective: Pregnancy at advanced maternal age has become more common over the last decades. Therefore, the study aimed to describe the characteristics and maternal and perinatal outcomes of women giving birth at advanced maternal age and very advanced age.
Methods: We conducted a retrospective cohort study of 2,300 singleton births that occurred in 2020-2021 at the Department of Gynaecology and Obstetrics of the Louis Pasteur University Hospital in Košice.
Ultrasound Obstet Gynecol
January 2025
Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Objectives: To examine the relationship of ophthalmic artery (OA) Doppler indices with uterine artery (UtA) Doppler indices, selected maternal hemodynamic parameters and gestational age, and to evaluate the intraobserver reproducibility of OA Doppler indices.
Methods: This was a prospective cohort study of women recruited between 11 + 0 and 23 + 6 weeks' gestation using a stratified and random sampling approach to ensure adequate distribution across the gestational-age range. OA pulsatility index (PI), first peak systolic velocity (PSV1), second peak systolic velocity (PSV2) and peak systolic velocity ratio (PSV ratio), calculated as PSV2/PSV1, were measured twice in each eye by the same observer.
J Womens Health (Larchmt)
January 2025
Division of General Internal Medicine, Department of Medicine, University of California at San Francisco, San Francisco, California, USA.
Despite health benefits to both infants and mothers, many are not breastfeeding as recommended by national guidelines. Prior studies examining the effects of housing insecurity and food insecurity on breastfeeding intention and duration have been limited and yielded mixed findings. To assess the relationship among housing insecurity, food insecurity, and breastfeeding, we conducted a secondary analysis of a cohort of nulliparous U.
View Article and Find Full Text PDFReprod Fertil
January 2025
M Mitra, Pediatrics, Institute of Child Health, Kolkata, 700017, India.
Threatened miscarriage is a common complication of early pregnancy characterized by symptoms of vaginal bleeding with/without abdominal cramps/pain in the first trimester. Progestogens are often administered for management of this condition. Presented herein is the protocol of an ongoing, multicentric clinical trial to investigate the efficacy and safety of micronized progesterone (natural progestogen) compared to dydrogesterone (synthetic isomer of progesterone).
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