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Apolipoprotein E epsilon4 allele is associated with better performance language and visual memory in spinocerebellar ataxia type 3.
Eur J Neurol
January 2025
School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
Background: The regulatory role of the apolipoprotein E (APOE) ε4 allele in the clinical manifestations of spinocerebellar ataxia type 3 (SCA3) remains unclear. This study aimed to evaluate the impact of the APOE ε4 allele on cognitive and motor functions in SCA3 patients.
Methods: This study included 281 unrelated SCA3 patients and 182 controls.
Phenomenological Mapping: A Method For Understanding Pre-Reflective Consciousness.
Integr Psychol Behav Sci
December 2024
Universidad del Desarrollo, Santiago de Chile, Chile.
Exploring the nuanced and often elusive realm of pre-reflective consciousness presents a methodological challenge, as it involves capturing experiences that arise prior to reflective thought and language. This article introduces Phenomenological Mapping, an innovative research method designed to systematically study the pre-reflective dimensions of human experience. Grounded in the foundational theories of Edmund Husserl (2012), Maurice Merleau-Ponty (2013), and Martin Heidegger (1992, 2008), the approach also integrates contemporary perspectives from Dan Zahavi (1999, Contemporary Phenomenology and Qualitative Research 5(1), 1-17, 2021), Shaun Gallagher (2006, 2017), and Evan Thompson (2010, 2017).
View Article and Find Full Text PDFMirror-invariance is not exclusively visual but extends to touch.
Sci Rep
December 2024
Department of Psychology, Jagiellonian University, ul. Ingardena 6, 30-060, Kraków, Poland.
Mirror-invariance enables recognition of mirrored objects as identical. During reading acquisition, sighted readers must overcome this innate bias to distinguish between mirror-inverted letters ('d' vs. 'b').
View Article and Find Full Text PDFLarge Language Models in Worldwide Medical Exams: Platform Development and Comprehensive Analysis.
J Med Internet Res
December 2024
Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Background: Large language models (LLMs) are increasingly integrated into medical education, with transformative potential for learning and assessment. However, their performance across diverse medical exams globally has remained underexplored.
Objective: This study aims to introduce MedExamLLM, a comprehensive platform designed to systematically evaluate the performance of LLMs on medical exams worldwide.
Psychometric evaluation and derivation of the Kannada version of the modified (29-item model) Indian Vision Function Assessment Questionnaire.
Indian J Ophthalmol
December 2024
Department of Ophthalmology, Yenepoya Deemed University, Karnataka, India.
Background/aims: India's linguistic and cultural diversity necessitates a region-specific validated Visual Functioning Questionnaire. The objective of this study was to translate the Indian Vision Function Questionnaire-33 (IND-VFQ-33) into the Kannada language and test its psychometric properties, underlying factor structure, and model fit.
Methods: A cross-sectional study was conducted among 330 participants, and basic psychometric properties (reliability, convergent, discriminant, construct validity, responsiveness, etc.
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