Functional electrical stimulation (FES) facilitates ambulatory function after paralysis of persons with spinal cord injury (SCI) by exciting the peripheral motor nerves to activate the muscles of the lower limbs. This study identified a process for selecting command sources for triggering FES with the surface electromyogram (EMG) from muscles partially paralyzed by incomplete SCI, given its high degree of intersubject variability. We found Discriminability Index (DI) to be a good metric to evaluate the potential of controlling FES-assisted ambulation in four nondisabled volunteers and two participants with incomplete paralysis. The left erector spinae (ES) (mean DI = 0.87) for triggering the left step and the right ES (mean DI = 0.83) for triggering the right step were the best command sources for participant 1. The left ES (mean DI = 0.93) for triggering the left step and the right medial gastrocnemius (mean DI = 0.88) for triggering the right step were the best command sources for participant 2. Our results showed that command sources can be selected objectively from surface EMG before a fully implantable EMG-triggered FES system for walking is implemented.

Download full-text PDF

Source
http://dx.doi.org/10.1682/jrrd.2010.08.0141DOI Listing

Publication Analysis

Top Keywords

command sources
20
selecting command
8
triggering left
8
left step
8
triggering step
8
step best
8
best command
8
sources participant
8
command
5
sources
5

Similar Publications

Large-scale Atomic/Molecular Massively Parallel Simulator (LAMMPS) is an open-source, powerful simulator with a customizable platform for extensive Langevin dynamics simulations. Here, we present a protocol for using LAMMPS to develop coarse-grained models of polymeric systems with macromolecular crowding, an integral part of any soft matter or biophysical system. We describe steps for installing software, using LAMMPS basic commands and code, and translocating polymers.

View Article and Find Full Text PDF

Identifying cancer prognosis genes through causal learning.

Brief Bioinform

November 2024

School of Artificial Intelligence, Jilin University, 3003 Qianjin Street, 130012 Changchun, China.

Accurate identification of causal genes for cancer prognosis is critical for estimating disease progression and guiding treatment interventions. In this study, we propose CPCG (Cancer Prognosis's Causal Gene), a two-stage framework identifying gene sets causally associated with patient prognosis across diverse cancer types using transcriptomic data. Initially, an ensemble approach models gene expression's impact on survival with parametric and semiparametric hazard models.

View Article and Find Full Text PDF

Emergency shelters are multifunctional spaces that provide safe refuge, essential life protection, and rescue command for residents in case of urban disaster. These shelters constitute crucial components of urban public safety. This study, with Tianhe District in Guangzhou City as a case study, used data from emergency evacuation sites and other socio-economic sources to construct an evaluation system for spatial suitability evaluation and layout optimization of emergency shelters.

View Article and Find Full Text PDF

Author Response: Insights into Immunomodulatory Therapy for Sepsis.

Indian J Crit Care Med

January 2025

Department of Medicine and Nephrology, Command Hospital (SC), Pune, Maharashtra, India.

Ghosh I, Sangha SS, Pandey G, Srivastava A. Author Response: Insights into Immunomodulatory Therapy for Sepsis. Indian J Crit Care Med 2025;29(1):91.

View Article and Find Full Text PDF

Prevalence of chronic kidney disease and anemia in Hirakud Command Area, Odisha, India: unveiling the role of environmental toxicants.

J Nephrol

January 2025

Laboratory of Renal Toxicopathology & Medicine, P.G. Department of Environmental Sciences, Sambalpur University, Burla, Odisha, 768019, India.

Background: The present community-based study assessed the prevalence of chronic kidney disease (CKD)/chronic kidney disease of unknown origin (CKDu) as well as anemia in some intense agricultural zones under Hirakud Command Area and evaluated their association with pesticides and heavy metal exposure.

Methods: Random cluster sampling method was used to assess the prevalence of CKD and anemia. Hematological analysis was carried out using autoanalyzer.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!