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The Long-Term Prognostic Outcomes of Emergent Colon Cancer Surgery: A Single-Center Experience.
Ann Ital Chir
December 2024
Department of General Surgery, Marmara University Pendik Training and Research Hospital, 34899 Istanbul, Türkiye.
Aim: Colorectal cancer (CRC) ranks as the second most diagnosed and third most deadly cancer worldwide. Despite advances in early diagnosis and treatment, CRC remains a leading cause of cancer-related deaths. Up to 30% of CRC patients are diagnosed during emergency department visits, leading to surgical procedures that may not adhere to oncological principles due to complications like obstruction, bleeding, or perforation.
View Article and Find Full Text PDFComparative meta-analysis of cold snare polypectomy and endoscopic mucosal resection for colorectal polyps: assessing efficacy and safety.
PeerJ
December 2024
The Second Affiliated Hospital, Soochow University, Soochow, China.
Colorectal polyps are commonly treated with surgical procedures, with cold snare polypectomy (CSP) and endoscopic mucosal resection (EMR) being the two most prevalent techniques. This meta-analysis (PROSPERO ID: CRD42022336152) aimed to compare the efficacy and safety of CSP and EMR in the management of colorectal polyps. Comprehensive searches were conducted in PubMed, Embase, CINAHL, Web of Science, and Cochrane Library databases, covering publications up until June 2024.
View Article and Find Full Text PDFThrough-the-scope tack application for defect closure following endoscopic submucosal dissection.
Tech Coloproctol
December 2024
Department of Colorectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, 9500 Euclid Avenue A-30, Cleveland, OH, 44195, USA.
Effective closure of both muscular and mucosal defects after endoscopic submucosal dissection (ESD) remains a technical challenge. Failure to adequately address such defects may increase the risk of delayed perforation. In this video case report, we demonstrate the application of the through-the-scope (TTS) tack system for defect closure following ESD in a patient with a cecal lesion.
View Article and Find Full Text PDFRisk factors for rectal perforation during presacral cyst removal: a comparison between transabdominal, perineal, and combined surgical approaches.
Tech Coloproctol
December 2024
Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.
Background: This study aimed to evaluate the risk factors associated with rectal perforation during various surgical interventions for presacral cysts.
Methods: This retrospective study included 73 participants from 2013 to 2023 who met the inclusion criteria. Participants underwent surgical treatments through transabdominal, perineal, or combined approaches.
Neoadjuvant Pembrolizumab in Stage I-III Deficient Mismatch Repair Colon Cancer: A Clinical Trial.
Ann Surg
December 2024
Department of Oncology, Rigshospitalet, Copenhagen, Denmark.
Objective: This clinical trial investigated the safety and efficacy of single-cycle pembrolizumab in patients with localized deficient mismatch repair (dMMR) colon cancer.
Background: Neoadjuvant immunotherapy has induced remarkable rates of pathological complete response in patients with dMMR colon cancer. However, the optimal length and type of treatment are yet to be determined.
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