The present paper reviews different possibilities of pharmacolegal residues in fish. Sometimes the treatment of fish with registered drugs in therapeutical dosage is provable in spite of keeping the withdrawal time. To that experiences of the persistence and values of Chloramphenicol, Chlortetracycline and Furazolidone proved after therapeutical treatment in fish correlated to the water temperature are compared with results of experiments documented in literature. Investigations on the residues of Enrofloxacin after application of different doses to rainbow trout were carried out. Sometimes the proof of drug residues in fish can be done without an advanced treatment. The recontamination of fish with drugs or their metabolites in environment is discussed as a possibility for drug residues. The carry-over-effect of drug during the animal food production can be also the reason for residues in fish. Experiments with Chloramphenicol contaminated feed in rainbow trout show residues in muscle of fish higher than 10 ppb during the feeding period. Finally the results of residues different drug used in fish--given in literature--are collected in two tables.
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Viruses
November 2024
Department of Aquaculture, Korea National University of Agriculture and Fisheries, Jeonju 54874, Republic of Korea.
Increasing antibiotic resistance poses an urgent global public health threat and a serious concern worldwide. Bacteriophage (phage) therapy has been identified as a promising alternative to antibiotics for treating bacterial diseases in both humans and animals. The excessive use of antibiotics in aquaculture is a major threat to sustainable aquaculture, promoting the spread of antibiotic resistance in the aquaculture environment and the contamination of aquaculture products with antibiotic residues.
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January 2025
State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
NLRP3 inflammasome activation is pivotal for cytokine secretion and pyroptosis in response to diverse stimuli, playing a crucial role in innate immunity. While extensively studied in mammals, the regulatory mechanisms governing NLRP3 activation in non-mammalian vertebrates remain largely unexplored. Teleosts, as basal vertebrates, represent an ideal model for exploring the evolutionary trajectory of inflammasome regulation.
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December 2024
School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China. Electronic address:
Tetracycline (TC) is widely used in veterinary medicine and animal feed; however, TC residues in food pose a risk to human health. Thus, the sensitive and selective detection of TC is needed to ensure food safety. Herein, we developed a CRISPR-Cas12a biosensor with competitive aptamer binding to detect TC residues.
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January 2025
Indian Council of Agriculture Research (ICAR)-Central Institute of Freshwater Aquaculture (CIFA), Fish Health Management Division, Bhubaneswar, Odisha, India.
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Int J Biol Sci
January 2025
Department of Biology, University of Padova, Padua, Italy.
Stat3 is a transcription factor with a key role in cell proliferation and migration. Using the zebrafish line we showed that the genetic ablation results in a marked decrease of tail fin regrowth, demonstrating that this transcription factor is fundamental in the regeneration process. Stat3 activity is finely modulated by post-translational modifications that occur in several residues of the protein (i.
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