Autism Spectrum Disorder (ASD) is more common than previously believed. ASD is increasingly diagnosed at very young ages. We report estimated ASD prevalence rates from a population study of 2-year-old children conducted in 2010 in Gothenburg, Sweden. Screening for ASD had been introduced at all child health centers at child age 21/2 years. All children with suspected ASD were referred for evaluation to one center, serving the whole city of Gothenburg. The prevalence for all 2-year-olds referred in 2010 and diagnosed with ASD was 0.80%. Corresponding rates for 2-year-olds referred to the center in 2000 and 2005 (when no population screening occurred) were 0.18 and 0.04%. Results suggest that early screening contributes to a large increase in diagnosed ASD cases.
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http://dx.doi.org/10.1007/s10803-011-1391-x | DOI Listing |
Histol Histopathol
January 2025
Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga, Punjab, India.
Autism spectrum disorder (ASD) is a globally recognized neurodevelopmental condition characterized by repetitive and restrictive behavior, persistent deficits in social interaction and communication, mental disturbances, etc., affecting approximately 1 in 100 children worldwide. A combination of genetic and environmental factors is involved in the etiopathogenesis of the disease, but specific biomarkers have not yet been identified.
View Article and Find Full Text PDFCureus
January 2025
Pharmacology, Mersin University, Mersin, TUR.
[This corrects the article DOI: 10.7759/cureus.74810.
View Article and Find Full Text PDFWorld J Gastrointest Oncol
January 2025
School of Life Health Information Science and Engineering, Chongqing Post and Communications University, Chongqing 400065, China.
This editorial, inspired by a recent study published in the , covers the research findings on microbiota changes in various diseases. In recurrent colorectal polyps, the abundances of , , and increase, while those of and decrease. This dysbiosis may promote the formation and recurrence of polyps.
View Article and Find Full Text PDFFront Child Adolesc Psychiatry
January 2024
National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Introduction: Regulatory problems of eating, sleeping, and crying in infancy may index mental health vulnerability in older ages, and knowledge is needed to inform strategies to break the developmental trajectories of dysregulation in early childhood. In this study, we examined the prospective associations between infant regulatory problems at the age of 8-10 months identified by community health nurses (CHN) and mental disorders diagnosed in hospital settings in children aged 1-8 years.
Methods: From a cohort of all newborn children in 15 municipalities in the Capital Region of Copenhagen ( = 43,922) we included all children who were examined by CHNs at the scheduled home visit at the age of 8-10 months ( = 36,338).
Theranostics
January 2025
Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
Mutations in the synaptic protein MAM domain containing glycosylphosphatidylinositol anchor 2 (MDGA2) have been associated with autism spectrum disorder (ASD). Therefore, elucidating the regulatory mechanisms of MDGA2 can help develop effective treatments for ASD. Liquid chromatography-tandem mass spectrometry was carried out to identify proteins interacting with the extracellular domain of RPS23RG1 and with MDGA2, followed by co-immunoprecipitation assays to confirm protein-protein interactions.
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