Apart from the direct influences of muscle spindle sensory endings on skeletomotor neurones a great deal of their reflex drive is provided indirectly via the gamma-loop. Fusimotor neurones modulate their discharge rate in parallel with that of the skeletomotor neurones during the rising phase, as well as during the maintained reflex tension in m.triceps surae of decerebrated cat, when small tension oscillations are present in the muscle. However, under other conditions of spinal reflex activities either skeletomotor or fusimotor neurones could be activated independently by impulses from muscle receptors. On the ground of the presented results, it can be supposed that fusimotor firing, together with the afferent firing from muscle spindles, does not provide the main stimulus for the reflex activity of skeletomotor neurones but serves as an indicator of the deviations from the expected or planned movement representing, in this way, its model.
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Annu Rev Vis Sci
September 2021
Graduate Center for Vision Research, SUNY College of Optometry, New York, New York 10036, USA; email:
The superior colliculus (SC) has long been associated with the neural control of eye movements. Over seventy years ago, the orderly topography of saccade vectors and corresponding visual field locations were discovered in the cat SC. Since then, numerous high-impact studies have investigated and manipulated the relationship between visuotopic space and saccade vector across this topography to better understand the physiological underpinnings of the sensorimotor signal transformation.
View Article and Find Full Text PDFJ Neurophysiol
April 2021
Department of Human Sciences, The Ohio State University, Columbus, Ohio.
Traumatic musculoskeletal injury (MSI) may involve changes in corticomotor structure and function, but direct evidence is needed. To determine the corticomotor basis of MSI, we examined interactions among skeletomotor function, corticospinal excitability, corticomotor structure (cortical thickness and white matter microstructure), and intermittent theta burst stimulation (iTBS)-induced plasticity. Nine women with unilateral anterior cruciate ligament rupture (ACL) 3.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
June 2020
Neurogastroenterology & Motility Center, Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261;
The central nervous system both influences and is influenced by the gastrointestinal system. Most research on this gut-brain connection has focused on how ascending signals from the gut and its microbiome alter brain function. Less attention has focused on how descending signals from the central nervous system alter gut function.
View Article and Find Full Text PDFCereb Cortex
April 2019
Department of Medicine and Surgery, University of Parma, Via Volturno 39, Parma, Italy.
Current knowledge regarding the processing of observed manipulative actions (OMAs) (e.g., grasping, dragging, or dropping) is limited to grasping and underlying neural circuitry remains controversial.
View Article and Find Full Text PDFJ Vet Med Sci
January 2019
Laboratory of Veterinary Anatomy, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
The midcingulate cortex (MCC; area 24') resides in the mid-rostrocaudal part of the cingulate gyrus, and it plays important roles in nociceptive, cognitive and skeletomotor functions. The MCC has recently been shown to consist of four cortical areas (areas a24a', a24b', p24a' and p24b') in the rabbit, based on immunohistochemistry. To further characterize the organization of these areas, here we immunohistochemically identified structures immunopositive (+) for calretinin (CR) as a marker of a subpopulation of inhibitory neurons.
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