The actual progress towards biological chip devices consisting of nanostructured functional entities is summarized. The practical aspects of molecular nanobiochips are discussed, including the main surface chemistry platforms, as well as conventional and unconventional fabrication tools. Several successful biological demonstrations of the first generation of nanobiochip devices (mainly, different nanoarrays) are highlighted with the aim of revealing the potential of this technology in life sciences, medicine, and related areas.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11114497 | PMC |
http://dx.doi.org/10.1007/s00018-011-0853-9 | DOI Listing |
Cell Mol Life Sci
February 2012
Department of Nanoengineering, Center for Physical Sciences and Technology, Savanorių 231, 02300 Vilnius, Lithuania.
The actual progress towards biological chip devices consisting of nanostructured functional entities is summarized. The practical aspects of molecular nanobiochips are discussed, including the main surface chemistry platforms, as well as conventional and unconventional fabrication tools. Several successful biological demonstrations of the first generation of nanobiochip devices (mainly, different nanoarrays) are highlighted with the aim of revealing the potential of this technology in life sciences, medicine, and related areas.
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