Effect of periodontal treatment on glycosylated hemoglobin levels in elderly patients with periodontal disease and type 2 diabetes.

Chin Med J (Engl)

Department of Periodontology, General Hospital of People's Liberation Army, Postgraduate Medical School, Beijing 100853, China.

Published: October 2011

Background: Periodontal disease is closely related to type 2 diabetes and is an important complication of diabetes. This study aimed to investigate the effect of periodontal treatment on levels of blood glucose (Glu) and glycosylated hemoglobin (HbA1c) among elderly patients with type 2 diabetes and periodontal disease.

Methods: A total of 107 elderly patients with type 2 diabetes and periodontal disease were selected and divided into two groups according to their HbA1c levels. Group A was a well-controlled diabetic group and group B was uncontrolled. Their probing depth (PD), attachment loss (AL), the value of Glu and HbA1c were analyzed before periodontal treatment and 4 months later.

Results: There was a significant difference in periodontal condition between groups A and B (P < 0.01). The periodontal condition for both groups was significantly (P < 0.01) improved after periodontal therapy. The effect of treatment in group A was more pronounced than group B, and the difference was significant (P < 0.01). After the periodontal treatment, Glu and HbA1c were reduced significantly in both groups (P < 0.05).

Conclusions: Periodontal condition is related to the control of Glu level among elderly patients with type 2 diabetes and periodontal disease. Periodontal treatment can effectively reduce the level of Glu and HbA1c as well as improve the periodontal condition in elderly type-2 diabetes patients with periodontal disease.

Download full-text PDF

Source

Publication Analysis

Top Keywords

periodontal treatment
20
periodontal disease
20
type diabetes
20
periodontal
16
elderly patients
16
periodontal condition
16
patients type
12
diabetes periodontal
12
glu hba1c
12
glycosylated hemoglobin
8

Similar Publications

Treponema denticola major surface protein (Msp): a key player in periodontal pathogenicity and immune evasion.

Arch Microbiol

January 2025

Department of Stomatology, The Second Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang, 421001, Hunan, China.

Treponema denticola, a bacterium that forms a "red complex" with Porphyromonas gingivalis and Tannerella forsythia, is associated with periodontitis, pulpitis, and other oral infections. The major surface protein (Msp) is a surface glycoprotein with a relatively well-established overall domain structure (N-terminal, central and C-terminal regions) and a controversial tertiary structure. As one of the key virulence factors of T.

View Article and Find Full Text PDF

Therapeutic potential of boric acid as a local drug delivery agent in periodontitis: a comprehensive systematic review and meta-analysis.

BMC Oral Health

January 2025

Oral Medicine, Periodontology, Diagnosis and Oral Radiology Department, Faculty of Dentistry, Mansoura University, Mansoura City, 33516, Egypt.

Objective: This systematic review and meta-analysis aim to evaluate the therapeutic potential of boric acid as a local drug delivery agent in the treatment of periodontitis.

Methods: Following PRISMA guidelines, we registered a comprehensive protocol with PROSPERO. By employing PICOS criteria, we evaluated randomized controlled trials assessing the effects of subgingival boric acid application alongside non-surgical periodontal therapy in treatment of periodontitis.

View Article and Find Full Text PDF

Metabolic syndrome and its effect on immune cells in apical periodontitis- a narrative review.

Clin Oral Investig

January 2025

Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, ON, M5G 1G6, Canada.

Objectives: Apical periodontitis (AP) is an inflammatory immune response in periapical tissues caused by microbial infections. Failure of root canal treatment or delayed healing is often due to intracanal or extra-radicular bacteria. However, beyond microbial factors, the patient's systemic health can significantly influence the progression and healing of AP.

View Article and Find Full Text PDF

Guidance on the assessment of the functionality of biomaterials for periodontal tissue regeneration: Methodologies and testing procedures.

Dent Mater

January 2025

Department of Cariology, Restorative Sciences and Endodontics, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, College of Engineering, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

Innovative biomaterials and tissue engineering strategies show great promise in regenerating periodontal tissues. This guidance provides an overview and detailed recommendations for evaluating the biological functionality of these new biomaterials in vitro, focusing on mineralization, immunomodulatory effects, cellular differentiation, and angiogenesis. Additionally, it discusses the use of in vivo experimental models that mimic periodontitis and scrutinizes methods such as osteogenic differentiation, immunomodulation, and anti-inflammatory responses to assess the effectiveness of these biomaterials in promoting periodontal tissue reconstruction.

View Article and Find Full Text PDF

Purpose: This retrospective clinical study aims to analyze single-unit implant-supported restorations' clinical and radiographic outcomes comprehensively.

Materials And Methods: In this retrospective study, patients who had undergone 12 months of implant-supported singleunit fixed prosthetic treatment were scanned from the archives, and a hundred patients were included in the study. Implant success and survival rates were assessed according to the consensus decisions published at the International Oral Implantology Congress in 2007.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!