A novel class of tartaric acid-derived N-spiro quaternary ammonium salts was synthesised starting from known TADDOLs. These compounds were found to catalyse the asymmetric α-alkylation of glycine Schiff bases with high enantioselectivities and in good yields.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202190PMC
http://dx.doi.org/10.1039/c1ob06573dDOI Listing

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