Synthesis and characterization of a template-assembled synthetic U-quartet.

Chem Commun (Camb)

Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, Canada BC V6T 1Z1.

Published: January 2012

A lipophilic cavitand containing four triazole-linked uridine residues has been synthesized and characterized. Spectral evidence suggests a quartet arrangement of the uracil residues at both ambient and low temperatures. Treatment of the compound with Sr(2+) yields a homodimeric complex as evidenced by NMR spectroscopy.

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Source
http://dx.doi.org/10.1039/c1cc15608jDOI Listing

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