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"Tension Chyle Leak": A Life-Threatening Sequela of Thoracic Duct Injury Following Resection of BRAF-Mutated Anaplastic Thyroid Carcinoma.
Head Neck
January 2025
Department of Otolaryngology Head and Neck Surgery, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
Background: Airway obstruction secondary to chyle leak is an exceptionally rare phenomenon. Here, we describe this complication in a patient with anaplastic thyroid carcinoma (ATC) undergoing consolidative surgery after BRAF-targeted therapy.
Methods: A 55-year-old man presented with a rapidly enlarging neck mass.
Background: Deficiency in the lysosomal enzyme, glucocerebrosidase (GCase), caused by mutations in the GBA1 gene, is the most common genetic risk factor for Parkinson's disease (PD). However, the consequence of reduced enzyme activity within neural cell sub-types remains ambiguous. Thus, the purpose of this study was to define the effect of GCase deficiency specifically in human astrocytes and test their non-cell autonomous influence upon dopaminergic neurons in a midbrain organoid model of PD.
View Article and Find Full Text PDFInfected pseudoaneurysm caused by suture-mediated vascular closure after ablation of atrial fibrillation: A case report.
Int J Surg Case Rep
January 2025
Department of Cardiology, Tosei General Hospital, Seto, Aichi, Japan.
Introduction: Suture-mediated vascular closure devices have been widely used in catheter ablation, with 0.14-0.3 % incidence of pseudoaneurysm complications.
View Article and Find Full Text PDFMaternal and Fetal Complications in Pregnant Women with Neurofibromatosis Type 1: Literature Review and Two Case Reports.
J Clin Med
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"Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Neurofibromatosis is a genetic disorder arising de novo or with an autosomal dominant transmission that typically presents either at birth or in early childhood, manifesting through distinctive clinical features such as multiple café-au-lait spots, benign tumors in the skin, bone enlargement, and deformities. This literature review aims to resume the spectrum of maternal and fetal complications encountered in pregnant women with neurofibromatosis type 1 (NF1). Thorough research was conducted on databases such as Web of Science, PubMed, Science Direct, Google Scholar, and Wiley Online Library.
View Article and Find Full Text PDFDesigning pillar-layered metal-organic frameworks with photo-induced electron transfer interactions between ligands for enhanced photodynamic sterilization and photocatalytic degradation of dyes and antibiotics.
J Colloid Interface Sci
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School of Chemistry and Chemical Engineering, Guangxi Key Laboratory of Electrochemical Energy Materials, Guangxi University, Nanning 530004 PR China. Electronic address:
Pollution caused by antibiotics, bacteria, and organic dyes presents global public health challenges, posing serious risks to human health. Consequently, new, efficient, fast, and simple photocatalytic systems are urgently required. To this end, 2,7-di(pyridin-4-yl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone (NDI)-an electron acceptor-is introduced as a connecting column into a porphyrin-based metal-organic layer (2DTcpp) with excellent photocatalytic activity; this modification yields a three-dimensional pillar-layered metal-organic framework (MOF, 3DNDITcpp) with superior photocatalytic reactive oxygen species (ROS) generation capability.
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