Introduction: This study evaluated whether leprosy reactions could be associated with oral infection.
Methods: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after elimination of the foci of infection.
Results: Group I presented more reactions than group II did, and improvement of the reactions after dental treatment. Serum CRP and IP-10 did not differ before and after the dental treatment, but differed between the groups.
Conclusions: Oral infection could be an exacerbating factor in leprosy reactions.
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| http://dx.doi.org/10.1590/s0037-86822011000500022 | DOI Listing |
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