Objective: Determining the prevalence and psychosocial factors associated with public university students' legal and illegal substance consumption.

Method: This was across-sectional study of 1,359 randomly selected students. The harvesting instrument included the CAGE questionnaire and VESPA,WHO, Rosenberg, Francis and APGAR scales. The Statistical Package for the Social Sciences (SPSS) was used for univariate and bivariate analysis using disparity ratios (95 % confidence intervals and 5 % error) whilst logistic regression was used for multivariate analysis.

Results: An association was found between abusive alcohol consumption and smoking cigarettes (OR=4.6), marijuana (OR=4.6) and using cocaine (OR=2.2); having a dysfunctional family was associated with smoking cigarettes (OR=1.2), using cocaine (OR=1.95) and abusive alcohol consumption (OR=1.94).

Conclusions: Abusive alcohol consumption and having a dysfunctional family were influential factors regarding psychoactive substance consumption in public university students.

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