Purpose: Evaluate the application of Hyperbaric Oxygen Therapy (HBO) in patients with Crohn's disease (CD) refractory to pharmacologic therapy, who developed abdominal, anorectal or skin complications.
Methods: Fourteen selected patients with refractory CD and treated at the School of Medicine of Ribeirao Preto, University of Sao Paulo (FMRP-USP) and at the Center of Hyperbaric Medicine, São Paulo Hospital (CEMEHI) were submitted to HBO.
Results: Of the 14 patients evaluated, 11 had a satisfactory response.
Conclusion: HBO has shown benefits in patients with CD refractory to pharmacologic therapy.
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