AI Article Synopsis
- Radiation optic neuropathy (RON) is a serious side effect of radiotherapy targeted at the anterior visual pathway, leading to severe and often permanent vision loss.
- RON typically occurs after receiving radiation doses over 50 Gy or more than 2 Gy in a single treatment, though certain conditions like diabetes can increase risk even at lower doses.
- A case study is presented where subacute RON developed following radiation for Graves' ophthalmopathy, which was effectively treated with high doses of intravenous corticosteroids.
Article Abstract
Radiation optic neuropathy (RON) is a devastating complication of radiotherapy to the anterior visual pathway resulting in acute, profound and sometimes irreversible visual loss. Cumulative doses of radiation that exceed 50 Gy or radiation fractions of greater than 2 Gy are usually required for RON to develop. Several factors, such as diabetes and pre-existing compression of the optic nerve, are associated with a higher risk for developing RON at lower doses of radiation. We report a case of presumed subacute RON following orbital irradiation for Graves' ophthalmopathy, successfully treated with megadoses of intravenous corticosteroids.
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| http://dx.doi.org/10.3109/01676830.2011.603458 | DOI Listing |
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