Surfaces presenting a heparin-binding peptide can non-covalently sequester heparin from culture supplements, such as fetal bovine serum. In turn, sequestered, serum-borne heparin can non-covalently localize growth factors at the cell-material interface, resulting in amplified growth factor bioactivity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410730PMC
http://dx.doi.org/10.1002/adma.201103046DOI Listing

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