General mechanism of actomyosin contractility.

Phys Rev Lett

Department of Physics, Washington University, One Brookings Drive, Campus Box 1105, St. Louis, Missouri 63130, USA.

Published: September 2011

Stress generation by myosin minifilaments is analyzed via simulation of their motion in a random actin network. The stresses are overwhelmingly contractile because minifilament equilibrium positions having contractile stress have lower energy than those for expansive stress. Force chains lead to unexpectedly large stresses.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226764PMC
http://dx.doi.org/10.1103/PhysRevLett.107.118101DOI Listing

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