Backgrounds: Thalassaemia is becoming serious public health problem throughout the Mediterranean region, Middle East, Indian subcontinents and also South East Asia. Its' global prevalence is about 2 per 1,000 newborns while its' prevalence in Iran is 8-4 per 1,000 newborns. The aim of this study was to compare the Health Related Quality of Life (HRQOL) of thalassaemia patients with the HRQOL of healthy children in terms of essential core domains for pediatric HRQOL measurement.
Methods: This cross sectional study has been done in Yazd, Iran. 60 thalassaemia patients were selected randomly as case group and 120 healthy children as control group who were matched with respect to age and gender. The health related quality of life was measured with a self - administrated short - form questionnaire of Medical Outcomes study (SF-20). The SF-20 measure contains three dimensions about function (physical, social and role) and well-being (mental health, health perception and pain).
Results: The results of this study showed significant difference between all dimension of SF-20 and QOL of patients in the case and control group (p<0.001). The QOL in the case group was 75.05 (SD=9.38), but in the control group was 93.4 (SD=6.42) out of 100.
Conclusions: The effect of thalassaemia on the HRQOL in affected children has been related to reduction of their physical, social and mental capabilities.
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http://dx.doi.org/10.21101/cejph.a3640 | DOI Listing |
Blood
January 2025
Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.
Over the last decade significant advances have been made by honing in on the diagnostic evaluation and the significance of molecular profiles in patients with systemic mastocytosis (SM), non-advanced and advanced.This is reflected in the 2022 iterations of the World Health Organization Edition 5 and International Consensus Criteria classifications.The impact of targeted KIT inhibitor therapies on patients treated within global trials has demonstrated significant improvements in the prognosis and overall survival for patients, leading to a change the treatment paradigm.
View Article and Find Full Text PDFJ Strength Cond Res
December 2024
Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Rome Open University, Rome, Italy; and.
Racil, G, Padulo, J, Trabelsi, Y, Frizziero, A, Russo, L, and Migliaccio, GM. Rhythmic exercises before basketball training: A study on motor skills, static balance, and reaction speed in school-aged children. J Strength Cond Res 38(12): e761-e768, 2024-The aim of this study was to investigate the effects of combining rhythmic exercises with basketball training on the improvement of basic motor and physical skills in children.
View Article and Find Full Text PDFJMIR Form Res
January 2025
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Background: The potential of telehealth psychotherapy (ie, the online delivery of treatment via a video web-based platform) is gaining increased attention. However, there is skepticism about its acceptance, safety, and efficacy for patients with high emotional and behavioral dysregulation.
Objective: This study aims to provide initial effect size estimates of symptom change from pre- to post treatment, and the acceptance and safety of telehealth dialectical behavior therapy (DBT) for individuals diagnosed with borderline personality disorder (BPD).
J Med Internet Res
January 2025
School of Management, Hefei University of Technology, Hefei, China.
Background: In online mental health communities, the interactions among members can significantly reduce their psychological distress and enhance their mental well-being. The overall quality of support from others varies due to differences in people's capacities to help others. This results in some support seekers' needs being met, while others remain unresolved.
View Article and Find Full Text PDFJ Trauma Nurs
January 2025
Author Affiliations: Department of Neurosurgery (Dr Xiao), Department of Nursing Care, Affiliated Hospital of Chengdu University, Chengdu, China (Dr Wang).
Background: Traditional nursing care often fails to meet the complex needs of hypertensive cerebral hemorrhage patients. Limited evidence exists on the efficacy of structured nursing frameworks such as the Omaha System in postoperative care for these patients.
Objective: This study aims to evaluate the efficacy of Omaha-based extended nursing care in improving patients' outcomes.
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