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A scoping review of human genetic resources management policies and databases in high- and middle-low-income countries.
BMC Med Ethics
March 2025
The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, 450008, China.
Background: This review examines global human genetic resources management, focusing on genetic data policies and repositories in high- and middle-low-income countries.
Methods: A comprehensive search strategy was employed across multiple databases, including official government websites and Google, to gather relevant literature on human genetic resources management policies and genetic resource databases. Documents were screened for relevance, focusing on high-income countries (United States, United Kingdom, Japan) and middle-low-income countries (China, India, Kenya).
Endoscopic treatment for gastroesophageal varices in patients with cirrhosis: a survey comparing between developed and developing countries.
BMC Gastroenterol
March 2025
Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, 28 Fuxing road, Haidian district, Beijing, 100853, China.
Background: In this survey, we compared endoscopists' approach to treatment of gastroesophageal varices (GOV) in patients with cirrhosis between developed and developing countries. The objective of this study was to undertake a comparative analysis of the approaches employed by endoscopists in developed and developing countries with regard to the treatment of GOV in patients with cirrhosis.
Methods: Between Jan 2019 to Aug 2019, we administered a questionnaire-based online survey internationally via e-mail.
Clinical Analyses of 4 Cases of Microsporidial Keratoconjunctivitis.
Acta Parasitol
March 2025
The Department of Ophthalmology, The Affiliated Eye Hospital of Nanjing Medical University, 138 Han-zhong Road, Nanjing, 210029, China.
Objective: To report four cases of microsporidial keratoconjunctivitis (MKC) from The Affiliated Eye Hospital of Nanjing Medical University (from May 2023 to October 2024) and to aid ophthalmologists in diagnosing and treating MKC, as MKC has been increasingly reported in Asian healthy individuals but not much in Mainland China.
Methods: Four patients with MKC were studied. Demographic information, symptoms, and clinical data were collected.
Granulomas are specialized biological defense mechanisms that form in response to infections with pathogens, foreign bodies, or specific stimuli such as antimicrobials or fungi. These structures function to isolate foreign materials and pathogens that cannot be eliminated by immune cells, primarily through macrophage activity. In the skin, granulomas are a hallmark of several conditions, including sarcoidosis, granuloma annulare, tuberculosis and leprosy, each exhibiting distinct pathological and immunological features.
View Article and Find Full Text PDFFrom Castaways to Discoveries: Unveiling Treasures in Skin RNAseq Using a Novel Multidimensional Data Processing Workflow Including Infection-Host Dynamics.
Physiol Genomics
March 2025
College of Human Medicine, Michigan State University, Grand Rapids, MI 49503 USA.
Defining physiology and methods to measure biological mechanisms is essential. Extensive datasets such as RNA sequencing are used with little analysis of the knowledge gained from the various methodologies. Within this work, we have processed publicly available NCBI RNAseq datasets using a combination of bioinformatics tools for the largest physiological organ, the skin.
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