The objective of this study was to evaluate the distribution of silver nanoparticles (NPs) in pregnant mice and their developing embryos. Silver NPs (average diameter 50 nm) were intravenously injected into pregnant CD-1 mice on gestation days (GDs) 7, 8, and 9 at dose levels of 0, 35, or 66 μg Ag/mouse. Mice were euthanised on GD10, and tissue samples were collected and analysed for silver content. Compared with control animals injected with citrate buffer vehicle, silver content was significantly increased (p < 0.05) in nearly all tissues from silver NP-treated mice. Silver accumulation was significantly higher in liver, spleen, lung, tail (injection site), visceral yolk sac, and endometrium compared with other organs from silver NP-treated mice. Furthermore, silver NPs were identified in vesicles in endodermal cells of the visceral yolk sac. In summary, the results demonstrated that silver NPs distributed to most maternal organs, extra-embryonic tissues, and embryos, but did not accumulate significantly in embryos.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/17435390.2011.626539 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Synthesis and characterization of innovative GA@Ag-CuO nanocomposite with potent antimicrobial and anticancer properties.
Sci Rep
January 2025
Department of Medical Laboratory Technology, Faculty of Applied Health Sciences Technology, Badr University in Cairo (BUC), Badr city, Cairo, Egypt.
Cancer and microbial infections place a significant burden on the world's health systems and can increase the rate of disease and mortality. In the current study, a novel nanocomposite based on Gum Arabic, silver and copper oxide nanoparticles (GA@Ag-CuO nanocomposite) was synthesized to overcome the problem of microbial infection and in cancer treatment. Characterization using UV-Vis.
View Article and Find Full Text PDFUltrasensitive detection of methylene blue by surface-enhanced Raman scattering (SERS) with Ag nanoparticle-decorated magnetic CoNi layered double hydroxides.
Anal Methods
January 2025
Key Laboratory of Oil and Gas Fine Chemicals Ministry of Education, Xinjiang Uyghur Autonomous Region, School of Chemical Engineering and Technology, Xinjiang University, Urumqi 830017, Xinjiang, China.
The unreasonable use of organic dye leads to excessive residues in environmental water, which seriously threatens human health and the natural environment. In this paper, a spherical flower-like magnetic FeO@CoNi layered double hydroxide@silver nanoparticle (FeO@CoNi LDH@Ag NPs) SERS substrate was successfully fabricated electrostatic self-assembly and applied for the sensitive detection of methylene blue (MB) in environmental water. The rapid concentration and separation of the SERS substrate from the water sample could be achieved using an external magnet.
View Article and Find Full Text PDFInvestigating the Synergistic Interactions Between AgNPs and NiCl on the Morpho-Physiological Trajectories of Zea mays L. Through Comprehensive Characterization at Seedling Stage.
Microsc Res Tech
January 2025
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Green synthesis of nanoparticles (NPs) is preferred for its affordability and environmentally friendly approach. This study explored the synthesis and characterization of silver NPs (AgNPs) and examined their impact on the growth of Zea mays, both alone and in combination with nickel chloride (NiCl). A methanolic leaf extract was combined with silver nitrate to synthesize AgNPs.
View Article and Find Full Text PDFPlasmon-enhanced visible photodetectors based on hexagonal boron nitride (hBN) with gold (Au), silver (Ag), and non-alloyed bimetallic (Au/Ag) nanoparticles.
Sci Rep
January 2025
Photonics Research Centre, Universiti Malaya, Kuala Lumpur, 50603, Malaysia.
Two-dimensional (2D) hexagonal boron nitride (hBN) has garnered significant attention due to its exceptional thermal and chemical stability, excellent dielectric properties, and unique optical characteristics, making it widely used in deep ultraviolet (DUV) applications. However, the integration of hBN with plasmonic materials in the visible region (532 nm) has not been fully explored, particularly in terms of morphology regulation and size control of mono- and bimetallic nanoparticles (BMNPs) namely gold (Au), silver (Ag) and Au-Ag. A Schottky junction-based metal-semiconductor contact configuration is employed to achieve hot-carrier reflections on the metal side, enhancing the quantum efficiency of the photodetector.
View Article and Find Full Text PDFFe-based nanostructured particles affect the biocontrol activity of Trichoderma species by inducing their effector-like and mycoparasitism-associated genes.
Chemosphere
December 2024
Centro de Investigación en Materiales Avanzados (CIMAV), Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chih., C.P. 31136, México. Electronic address:
The use of biocontrol microorganisms is one of the primary techniques used in agriculture to combat the damage caused by phytopathogens. Of these, Trichoderma sp. stand out as fungi species that are naturally present in agricultural soil and can come into contact with various compounds, such as nanostructured particles (NPs), which are starting to be used as pesticides and fertilizers.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!