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| http://dx.doi.org/10.1093/cid/cir688 | DOI Listing |
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Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases.
Rev Paul Pediatr
January 2025
Universidade Federal de Goiás, Institute of Tropical Pathology and Public Health, Parasite-Host Relationship Studies Laboratory, Goiânia, GO, Brazil.
Objective: To describe two severe cases of congenital toxoplasmosis in infants born to chronically infected mothers who did not receive education or information on the prevention of gestational toxoplasmosis during prenatal care.
Case Description: The mothers had a previous serological diagnosis of toxoplasmosis conducted during prenatal care, with non-reactive (<10 IU/mL) IgM and reactive IgG (>10 IU/mL), and were considered "immune" to the infection. Both infants were born with sequelae of the congenital infection, including neurological and ocular alterations.
Current and Emerging Techniques for Diagnosis of Toxoplasmosis in Pregnancy: A Narrative Review.
Iran J Parasitol
January 2024
Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran.
is an intracellular parasite capable of crossing the placenta in pregnancy and infecting the developing fetus, leading to various congenital anomalies and even abortion. Acute infection is responsible for almost all cases of congenital toxoplasmosis in immunocompetent pregnant women. Prenatal screening for acute toxoplasmosis primarily involves maternal serology and fetal ultrasound imaging.
View Article and Find Full Text PDFImpact of chronic toxoplasmosis in pregnancy: Association between maternal IgG antibodies against T. gondii and neurocognitive development effects.
Neurotoxicology
January 2025
Graduate Program in Pharmacy, College of Pharmacy, Federal University of Bahia, Salvador, Bahia, Brazil; Laboratory of Toxicology, College of Pharmacy, Federal University of Bahia, Salvador, Bahia, Brazil; Graduate Program in Public Health, Federal University of Bahia, Salvador, Bahia, Brazil.
Toxoplasmosis presents notable hazards in the context of pregnancy, impacting the health of the mother and the neurodevelopment of the fetus via immune reactions and possible vertical transmission. The maternal immune response from chronic Toxoplasma gondii (T. gondii) infection may negatively influence fetal neurodevelopment.
View Article and Find Full Text PDFSeroprevalence of and Associated Risk Factors in Pregnant Women in Araçatuba, São Paulo, Brazil: A Multi-Level Analysis.
Microorganisms
October 2024
Faculdade de Medicina Veterinária, Universidade Estadual Paulista (UNESP), Araçatuba 16050-680, SP, Brazil.
This study assessed the seroprevalence of and risk factors among 428 pregnant women attending Basic Health Units (BHUs) in Araçatuba, São Paulo, Brazil. The seroprevalence was 55.14%, indicating high exposure to the parasite in this population.
View Article and Find Full Text PDFIsolated Fetal Liver Calcifications: Case Report and Literature Review.
J Clin Ultrasound
January 2025
Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Article Synopsis
- - Fetal liver calcifications (FLCs) are areas of increased echogenicity in the fetal liver, occurring in about 5-10 per 10,000 births, and while often associated with various health issues, isolated cases typically have a good prognosis.
- - The article discusses a case of a 29-year-old woman with a normal first-trimester screening who later showed FLCs during her 20-week scan without any other fetal problems.
- - After thorough monitoring and testing throughout her pregnancy, she delivered a healthy male baby, and subsequent evaluations confirmed his good health, highlighting the positive outcomes related to isolated FLCs.
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