Various cueing techniques as well as treadmill training have been shown to be effective in the gait rehabilitation of patients with Parkinson disease. We present a novel setup combining both dynamic visual cueing and body weight-supported treadmill training. A nonambulatory patient with Parkinson disease received six training sessions. Continuous improvement of gait parameters was observed throughout the course of training. When comparing cued and noncued conditions in individual training sessions, it was found that step length was larger and that gait symmetry was enhanced in the cued condition. At the end of the training period, the patient was capable of walking short distances with a walking frame. In conclusion, dynamic visual cueing in combination with body weight-supported treadmill training seems to be a promising treatment strategy for patients with Parkinson disease, even in the case of severe impairment.
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http://dx.doi.org/10.1097/PHM.0b013e3182389fe2 | DOI Listing |
Rev Med Suisse
January 2025
Service de neurologie, Clinique bernoise Montana, 3963 Crans-Montana.
Parkinson's disease affects around 6 million people worldwide. It causes both motor and non-motor symptoms. Since there is no cure, medical treatment aims to improve patients' quality of life.
View Article and Find Full Text PDFFront Physiol
January 2025
China Institute of Sport and Health Science, Beijing Sport University, Beijing, China.
This study aims to assess the reliability and accuracy of a novel portable cardiopulmonary function meter, "Booster," developed by our research group, across various exercise intensities and modalities. The study was segmented into reliability and validity assessments. Twenty-two male participants underwent reliability testing, conducting two sequential tests on a treadmill while wearing the Booster to measure VO and VE among other parameters at increasing intensities.
View Article and Find Full Text PDFFront Neurosci
January 2025
Department of Physical Therapy, China Medical University, Taichung, Taiwan.
Introduction: Parkinson's disease (PD) is characterized by progressive neurodegeneration within the nigrostriatum, leading to motor dysfunction. This systematic review aimed to summarize the effects of various exercise training regimens on protein or gene expression within the nigrostriatum and their role in neuroprotection and motor function improvement in animal models of Parkinson's disease (PD).
Methods: PubMed, EMBASE, and Web of Science were searched up to June 2024 and included sixteen studies that adhere to PRISMA guidelines and CAMARADES checklist scores ranging from 4 to 6 out of 10.
Animal Model Exp Med
January 2025
School of Rehabilitation, Capital Medical University, Beijing, China.
Background: The inability of damaged neurons to regenerate and of axons to establish new functional connections leads to permanent functional deficits after spinal cord injury (SCI). Although astrocyte reprogramming holds promise for neurorepair in various disease models, it is not sufficient on its own to achieve significant functional recovery.
Methods: A rat SCI model was established using a spinal cord impactor.
Nat Commun
January 2025
Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China.
Physical exercise effectively prevents anxiety disorders caused by environmental stress. The neural circuitry mechanism, however, remains incomplete. Here, we identified a previously unrecognized pathway originating from the primary motor cortex (M1) to medial prefrontal cortex (mPFC) via the ventromedial thalamic (VM) nuclei in male mice.
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