Objective: To investigate the possible presence of infection in necrotic nonsalvageable testes of patients presenting with testicular torsion and to question the rationale for deferring orchiopexy in such situations to a later date.
Material And Methods: Between 2003 and 2011, 16 consecutive patients underwent same-time contralateral orchiopexy and ipsilateral orchiectomy for testicular torsion with necrosis. In all cases, peritesticular fluid or aspirate directly from the necrotic testes was investigated with Gram staining and culturing. The patients were followed at 1 and 3 months after operation for infection of the scrotal incision, or of the remaining testis.
Results: The median age of the patients was 17 years (range 13-32) and the duration of illness ranged from 3-17 days. Both Gram staining and culturing of the peritesticular fluid or testicular aspirate failed to reveal the presence of pathogenic organisms. On follow-up at 1 and 3 months, there was no clinically evident infection of the scrotal incision, or of the remaining testis.
Conclusion: In cases where testicular torsion with necrosis dictates that unilateral orchiectomy must be done, there is no evidence to suspect the presence of bacterial infection in the necrotic testis or surrounding fluid. There is no evidence that one-stage surgery--ipsilateral orchiectomy and contralateral orchiopexy--carries a risk of clinically evident infection related to the necrotic testis and as such patients should be offered one-stage surgery. Continuous and sustained effort should be made toward assuring that testicular torsion receives timely assessment and referral to qualified medical personnel.
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http://dx.doi.org/10.1016/j.urology.2011.08.059 | DOI Listing |
J Reprod Infertil
January 2024
Department of Toxicology and Pharmacology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
Background: Testicular torsion is a critical urological emergency that can lead to testicular ischemia and significant tissue damage. Citrulline, a supplement known for enhancing cellular metabolism and mitigating oxidative stress and inflammation, has been explored for its protective effects against testicular injury resulting from torsion and detorsion in rat models.
Methods: This study involved 42 Wistar rats, divided into six groups: Sham, torsion/detorsion (T/D), and four groups receiving varying doses of Citrulline (300, 600, 900 ) and vitamin E (20 ).
Vet Res Forum
December 2024
Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Testicular ischemia-reperfusion (I/R) injury during testicular torsion is strongly influenced by oxidative stress caused by excessive accumulation of unscavenged reactive oxygen species. This study aimed to investigate the effects of intra-peritoneal administration of Mito-TEMPO (MT) on I/R injury in testicular torsion/detorsion (T/D) in mice. Forty-two male mice were divided into seven groups including 1 control and 6 treatment groups (360° T/D, 720° T/D, 360° T/D + 0.
View Article and Find Full Text PDFUrology
January 2025
Institute for Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Objectives: To assess torsion outcomes and evaluates the rate of testicular atrophy.
Methods: The study was done over the 2000-2024 period during which 103 patients of average age 12.9± 3.
Turk J Pediatr
November 2024
Division of Pediatric Immunology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Background: Griscelli syndrome (GS) is a rare genetic disorder characterized by oculocutaneous albinism and variable immune dysfunction. Among three distinct types of GS, occurring due to different genetic mutations; GS type 1 presents with neurological manifestations, hemophagocytic lymphohistiocytosis (HLH) generally develops in GS type 2, and GS type 3 primarily exhibits oculocutaneous albinism. HLH, a life-threatening condition with excessive immune activation, may occur secondary to various triggers, including infections, and develop in different tissues, as well as in the testis, similar to Erdheim-Chester disease.
View Article and Find Full Text PDFInt J Urol
January 2025
Department of Urology, Tel Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel.
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