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Novel use of ultrasound-guided high-intensity focused ultrasound (HIFU) may enable the neuroablation of the sacroiliac joint in a swine model: a feasibility study.
Reg Anesth Pain Med
January 2025
Department of Anesthesiology & Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Background: Sacroiliac joint (SIJ) dysfunction accounts for the etiology of pain in 15%-30% of low back pain cases. Some patients with conservative treatment-refractory SIJ dysfunction undergo radiofrequency (RF) ablation of the SIJ for prolonged pain relief. This procedure involves placing up to 12 RF probes in what is an invasive, resource-intensive, and time-consuming process.
View Article and Find Full Text PDFReproductive outcomes of high-intensity focused ultrasound ablation and myomectomy for uterine fibroids: a systematic review and meta-analysis.
Reprod Biomed Online
September 2024
Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Fudan University, Shanghai, China.; Research Institute, Shanghai Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.. Electronic address:
Article Synopsis
- A systematic review and meta-analysis was conducted to compare reproductive outcomes of high-intensity focused ultrasound (HIFU) ablation and myomectomy for patients with uterine fibroids up to March 2024.
- Results showed that HIFU treatment had significantly lower pregnancy (23.3%) and live birth rates (17.3%) compared to myomectomy (56.9% pregnancy and 44.1% live birth rates), suggesting myomectomy is more effective.
- The study highlights the need for better quality research on HIFU and calls for more comparative trials against myomectomy to improve understanding of reproductive outcomes in women with uterine fibroids.
Ultrasound-guided high-intensity focused ultrasound for symptomatic uterine fibroids: clinical outcome of two European centers.
Eur Radiol
November 2024
Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
Objectives: The aim of this study is to assess the clinical outcome and mid-term efficacy of ultrasound-guided high-intensity focused ultrasound (USgHIFU) as a treatment for symptomatic uterine fibroids at two major European HIFU centers.
Materials And Methods: This bi-center longitudinal clinical study involved the treatment of 100 patients with symptomatic uterine fibroids using USgHIFU (n = 59 in Germany, n = 41 in Bulgaria). Clinical outcomes were evaluated at 6 weeks, 6 months, and 1 year follow-up utilizing the uterine fibroid symptoms-quality of life questionnaire for fibroid-related symptoms and health-related quality of life as well as MRI imaging for determining the fibroid volume.
Ultrasound-Guided High-Intensity Focused Ultrasound Combined With PD-1 Blockade in Patients With Liver Metastases From Lung Cancer: Protocol for a Single-Arm Phase 2 Trial.
JMIR Res Protoc
November 2024
Respiratory Department, Xiangtan Central Hospital, Xiangtan, China.
Background: While immunotherapy has revolutionized oncological management, its efficacy in lung cancer patients with liver metastases remains limited, potentially due to the unique immunosuppressive microenvironment of the liver. Local liver treatment has been shown to enhance the immunotherapy response, and high-intensity focused ultrasound (HIFU), a minimally invasive local treatment, has demonstrated promising results in combination with immunotherapy. However, clinical data regarding HIFU in lung cancer with liver metastases are limited.
View Article and Find Full Text PDFDiagnostic dilemma: a collision of pancreatic neuroendocrine tumor G3 and adenocarcinoma with extensive fibrosis.
Clin J Gastroenterol
November 2024
Department of Gastroenterology, Toyonaka Municipal Hospital, Toyonaka, Osaka, 565-0871, Japan.
Article Synopsis
- * Further tests, including endoscopic ultrasound and histopathological analysis, revealed the mass was actually a grade 1 neuroendocrine tumor (NET), changing the diagnosis before surgery.
- * After surgery, the pathology showed a mixed tumor containing both NET (Grade 1 and Grade 3) and invasive PDAC, illustrating the complexity of accurately diagnosing mixed tumors preoperatively due to overlapping features.
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