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Background: There is continuous demand for safe, effective cosmetic ingredients to treat the signs of aging skin, including fine lines, wrinkles, brown spots, discoloration, laxity, and sagging. While there are a plethora of cosmeceutical peptides, few combine anti-aging and anti-inflammatory benefits with small size.
Methods: Preclinical and clinical studies evaluated the anti-inflammatory properties, anti-aging benefits, and tolerability of acetyl dipeptide-31 amide (AP31), a novel, small, anti-aging micropeptide, to understand its impact as a multifaceted, cosmetic, anti-aging, and anti-inflammaging ingredient.
The FEDBD plasma's quantitative investigation of skin parameters: Skin elasticity, thickness, density, tissue oxygenation, perfusion, and edema.
Heliyon
January 2024
Laser-Plasma Research Institute, Shahid Beheshti University, G.C., P.O. Box, 19839-6941, Tehran, Iran.
This study used the FEDBD plasma device for skin rejuvenation in animal samples. There were two groups of six male Wistar rats. Before starting the treatment, immediately after the treatment, the fourth week, and the tenth week of follow-up, biometric tests were performed, including moisture level, evaporation from the skin surface, erythema and melanin, skin elasticity and firmness with an MPA9 device and cutometer.
View Article and Find Full Text PDFCombined Gluteal and Posterior Thigh Compartment Syndrome Without Associated Fracture: A Case Report.
J Clin Med Res
April 2022
Department of General Medicine, Saint Helena General Hospital, Jamestown, STHL 1ZZ Saint Helena, South Atlantic Ocean, UK.
Compartment syndrome usually occurs after trauma, fracture, or compression injuries. To the authors' best knowledge, this is the first reported case in the medical literature of a combined gluteal and posterior thigh compartment syndrome after an accidental fall without an associated fracture. A 65-year-old man attended the emergency department of the general hospital in a remote island complaining of a swollen painful thigh.
View Article and Find Full Text PDFHard bilateral syphilitic testes with vasculitis: a case report and literature review.
BMC Urol
September 2021
Department of Urology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-Ku, Tokyo, 142-8555, Japan.
Background: We report the case of a patient with syphilitic testicular gumma and vasculitis with adrenal failure due to chronic steroid use.
Case Presentation: A 63-year-old male presented with hard right eye swelling and very firm bilateral testes on palpation, which he had for 2 years. Testicular tumor markers were negative; syphilis test was positive.
Laser-Assisted Hyaluronic Acid Delivery by Fractional Carbon Dioxide Laser in Facial Skin Remodeling: A Prospective Randomized Split-Face Study in France.
Lasers Surg Med
November 2021
Dermatologic Laser Center, Hôpital de la Conception, Aix-Marseille Univ., APHM, 13005, Marseille, France.
Background And Objectives: Combining the efficacy of ablative fractional carbon dioxide lasers (AFXL) to laser-assisted hyaluronic acid delivery (LAHAD) has not yet been studied. The objective of our study was to evaluate the safety and the efficacy of laser-assisted hyaluronic acid (HA) delivery with AFXL in facial skin remodeling.
Study Design/materials And Methods: We conducted a prospective, double-blinded, randomized split-face study on 20 patients from 30 to 70 years old, with a skin phototype from I to IV.
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