Purpose: The purpose of this cadaveric study was to study the effect of plane of osteotomy on incidence of lateral cortex fracture and to define a "safe zone" through which medial open-wedge high tibial osteotomy (HTO) could be performed with minimal risk of lateral cortex fracture.
Methods: Medial open HTO was performed in nine fresh frozen human cadavers (18 knees) with each specimen randomly assigned to a "safe zone" osteotomy (group A, between the tip of the fibular head and the circumference line of the fibular head), or a lower level osteotomy (group B, distal to the circumference line of the fibular head).
Results: Six out of nine knees developed lateral cortex fracture in group B compared to none in group A (P = 0.009) when the osteotomy site was distracted to a maximum of 20 mm.
Conclusion: Directing the plane of the osteotomy toward the "safe zone" significantly reduces the risk of lateral cortex fracture compared to an osteotomy, which is directed at a lower level. Confining the plane of a medial open HTO to within the "safe zone" can prevent lateral cortex fracture and subsequent loss of correction.
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http://dx.doi.org/10.1007/s00167-011-1706-7 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Department of Psychology, Vanderbilt University, Nashville, TN 37240.
Lesions of the dorsal columns of the spinal cord in adult macaque monkeys lead to the loss of hand inputs and large-scale expansion of the face inputs in the hand region of the somatosensory cortex. Inputs from alternate spinal pathways do not reactivate the deafferented regions of area 3b. Here, we determined how transections of the dorsal columns done within a few days after birth affect the developing somatosensory cortex.
View Article and Find Full Text PDFClin Neurophysiol Pract
December 2024
Department of Rehabilitation Medicine, Shanghai Jing'an District Central Hospital, Shanghai, China.
Objective: To elucidate the immediate electrophysiological effects of mirror visual feedback (MVF) combined with or without touch task in subacute stroke.
Methods: Subacute stroke patients and healthy controls were recruited to participate in four grasping tasks (MVF or no MVF, combined with rubber ball or no ball) under electroencephalogram (EEG) monitoring. Event-related desynchronization (ERD) /event-related synchronization (ERS) and the lateralization index (LI) were utilized to observe the electrophysiological effects.
Nat Commun
January 2025
Department of Experimental Psychology, University of Oxford, Oxford, UK.
When we collaborate with others to tackle novel problems, we anticipate how they will perform their part of the task to coordinate behavior effectively. We might estimate how well someone else will perform by extrapolating from estimates of how well we ourselves would perform. This account predicts that our metacognitive model should make accurate predictions when projected onto people as good as, or worse than, us but not on those whose abilities exceed our own.
View Article and Find Full Text PDFJ Affect Disord
January 2025
Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China. Electronic address:
Aims: We aimed to determine the relationship between altered brain imaging characteristics, cognitive function and profiles of gene expression of bipolar disorder (BD).
Methods: Functional magnetic resonance imaging (fMRI) was presented in three groups of BD participants (depressed, manic and euthymic) and healthy controls. Regional Homogeneity (ReHo) and region of interest based functional analysis combining with neuroimaging-transcription association analysis were utilized to investigate abnormalities and their correlation with clinical symptoms.
Eur J Neurosci
January 2025
Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
Communication sound processing in mouse AC is lateralized. Both left and right AC are highly specialised and differ in auditory stimulus representation, functional connectivity and field topography. Previous studies have highlighted intracortical functional circuits that explain hemispheric stimulus preference.
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