Unlabelled: In a clinical follow-up of our therapeutic results for popliteal artery repair, there were 2 recurrences. Angiomorphologically the results could be classified as an endoleak type II form.
Method: In a retrospective analysis of 56 popliteal artery aneurysms in our vascular surgery department between September 2000 and 2010, 47 cases underwent surgical and 9 cases endovascular repair. The average age of the patients was 70.2 years (49-88 years); males were in the majority (92.8 %) in comparison to females (7.2 %). In the ambulatory follow-up, 2 patients that had had surgery showed an increase in size of the operated popliteal artery. Duplex sonography, angio-CT scan and selective angiography were used to verify the results.
Results: 47 cases were treated with surgical repair. In 42 cases a proximal and distal surgical exclusion with ligation of the aneurysm was performed via a medial approach. In 5 cases a dorsal approach was used for the aneurysmectomy. In the post-operative follow-up period 2 surgically repaired popliteal aneurysms showed persistent reperfusion. In both these cases the medial approach was chosen, leaving the aneurysm in situ. The reperfusion was proved with the help of an angio-CT scan. A selective DSA (Doppler sonography) confirmed the results. Both recurring aneurysms were re-operated firstly due to the increase in size and secondly due to the diagnosis of an imminent rupture.
Conclusion: The retrospective analysis showed that in the follow-up 2 (3,6 %) primarily repaired popliteal aneurysms had a recurrence with an increase in size. They were both repaired via a medial approach. In both cases the recirculation was diagnosed via the geniculate vessels. According to the endoleak classification of endovascularly repaired aortic aneurysms, the diagnosis is equivalent to an endoleak type II classification. [nl]The ligation alone, without the occlusion of the geniculate branches, lead to a persistent back flow and reperfusion with increase in size of the aneurysms. The therapeutic option of such recurrences, due to the presence of active genicular recirculation ought to be the occlusion of these vessels that supply the aneurysm. The safest method to prevent such recurrences is without doubt the extirpation, the aneurysmo-endorraphy as well as the proximal and distal ligation, that definitely occludes the genicular vessels. As a rule the duplex sonography examination is advisable to control repaired popliteal aneurysms in situ.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1055/s-0031-1283776 | DOI Listing |
Med Phys
January 2025
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Background: The spatial resolution of new, photon counting detector (PCD) CT scanners is limited by the size of the focal spot. Smaller, brighter focal spots would melt the tungsten focal track of a conventional X-ray source.
Purpose: To propose focal spot multiplexing (FSM), an architecture to improve the power of small focal spots and thereby enable higher resolution clinical PCD CT.
BMC Cardiovasc Disord
January 2025
Department of Cardiology, Northern Jiangsu People's Hospital, Nantong West Road No. 98, Yangzhou, Jiangsu, 225001, China.
Objectives: The aim of this study was to explore the correlation between blood test indicators and Atrial Fibrillation (AF) in Individuals Aged 65 and Older in Yangzhou, Jiangsu.
Methods: From January 1, 2019, to August 31, 2023, an epidemiological cross-sectional survey was conducted among the elderly population undergoing health check-ups at Northern Jiangsu People's Hospital in Jiangsu Province. Patients diagnosed with AF after a 12-lead electrocardiogram were included in the case group, and non-AF individuals matched by age and gender in a 1:4 frequency ratio were included in the control group.
Sci Rep
January 2025
Thoracic and Vascular Surgery Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Abdominal Aortic Aneurysm (AAA) poses a significant health risk due to its silent nature and high mortality upon rupture. The Fib-4 index, initially designed for liver fibrosis assessment, presents potential beyond its scope. This study aims to investigate the association of FIB-4 with aneurysm size and mortality risk, exploring its utility as a risk predictor for enhanced clinical management.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Heidelberg, Germany.
Pathological cardiac remodeling is a maladaptive response that leads to changes in the size, structure, and function of the heart. These changes occur due to an acute or chronic stress on the heart and involve a complex interplay of hemodynamic, neurohormonal and molecular factors. As a critical regulator of cell growth, protein synthesis and autophagy mechanistic target of rapamycin complex 1 (mTORC1) is an important mediator of pathological cardiac remodeling.
View Article and Find Full Text PDFNPJ Breast Cancer
January 2025
Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Endocrine therapy with CDK4/6 inhibitors is standard for estrogen receptor-positive, HER2-negative metastatic breast cancer (ER+/HER2- MBC), yet clinical resistance develops. Previously, we demonstrated that low doses of palbociclib activate autophagy, reversing initial G1 cell cycle arrest, while high concentrations induce off-target senescence. The autophagy inhibitor hydroxychloroquine (HCQ) induced on-target senescence at lower palbociclib doses.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!