AI Article Synopsis

  • - The study aimed to evaluate changes in macular thickness after two types of keratoplasty (PKP and DALK) for keratoconus using optical coherence tomography.
  • - It analyzed 60 eyes from 60 patients, measuring macular thickness before surgery and at 1, 3, and 6 months post-operation, finding no significant differences between the two surgical approaches in terms of thickening.
  • - Results indicated that both PKP and DALK led to increased macular thickness over time, with 43.2% of PKP and 50.0% of DALK cases showing over 10% thickening, suggesting both techniques similarly affect the macula.

Article Abstract

Purpose: The aim of this study was to assess changes in macular thickness by means of optical coherence tomography after penetrating keratoplasty (PKP) and deep anterior lamellar keratoplasty (DALK) for keratoconus.

Methods: This prospective study comprised 60 eyes of 60 patients who had keratoplasty for the treatment of keratoconus. Eyes were divided into 2 groups according to the keratoplastic technique applied: PKP group and DALK group. Measurements of central macular thickness were performed preoperatively and 1, 3, and 6 months after surgery.

Results: The final analysis included 33 eyes in the PKP group and 24 eyes in the DALK group. In the PKP group, the central macula was found to be 6.5%, 6.3%, and 4.5% thicker in the first, third, and sixth month, respectively. Similarly, the central macula was 5.6%, 5.4%, and 2.9% thicker at months 1, 3, and 6 in the DALK group. The 2 groups did not differ significantly in terms of macular thickening. The percentage of eyes showing more than 10% increase in the macular region at any time during the follow-up period was 43.2% in the PKP group and 50.0% in the DALK group (P = 0.614). The percentage of eyes found to have a central macular thickness more than 250 μm at any time during the follow-up period was 10.8% in the PKP group and 18.2% in the DALK group (P = 0.424).

Conclusions: The study showed that DALK, although it is a closed-system technique, has a similar impact on the macula compared with PKP.

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Source
http://dx.doi.org/10.1097/ICO.0b013e31821eeaadDOI Listing

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