Thyroid orbitopathy may result in significant proptosis that causes visual lost. Besides pharmacologic and radiotherapeutic procedures surgically decompression of the orbital skeleton occasionally is managed. We present series of 3 patients (5 procedures) who underwent orbital decompressions. The preoperative proptosis ranged from 22 to 31mm. Decompression was performed by an external Walsh-Ogura approach in 3 orbits and in 2 by an endoscopic approach. The reduction in proptosis was 4-6mm in external approach cases and 4-5mm in endoscopic procedures. Diplopia was noted in 2 patients preoperatively, and no one had new postoperative diplopia. Surgical orbital decompression is occasionally necessary procedure or visual lost rescue in thyroid orbitopathy and in cases of diplopia can not improve muscular function. Endoscopic surgery is a safe and effective management in moderate proptosis. Autoimmunologic inflammatory changes in nasal mucosa do not increase postoperative complication risk.
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http://dx.doi.org/10.1016/S0030-6657(11)70687-4 | DOI Listing |
Ann Endocrinol (Paris)
January 2025
Department of endocrinology and metabolic diseases, pôle cardio-vasculaire et métabolique, CHU Larrey, 24, chemin de Pouvourville, TSA 30030, 31059 Toulouse, France. Electronic address:
Radiol Bras
December 2024
Radiologist at the Instituto do Câncer do Estado de São Paulo (ICESP) and for the Grupo Dasa, São Paulo, SP, Brazil. Email:
Radiol Bras
December 2024
Faculdade de Medicina de Botucatu, Universidade Estadual Paulista "Júlio de Mesquita Filho" (Unesp), Botucatu, SP, Brazil.
Objective: To assess the prevalence of changes on computed tomography (CT) in Graves' orbitopathy (GO) and to correlate those changes with disease activity, as well as with clinical and biochemical variables.
Materials And Methods: This was a retrospective study, conducted at a tertiary hospital, of clinical, biochemical, and imaging data from consecutive patients with GO who underwent at least one orbital CT scan between July 2012 and December 2020. A single observer quantified the thickness of the extraocular muscles and the degree of proptosis.
Mol Imaging Biol
January 2025
Department of Nuclear Medicine (PET Center), Key Laboratory of Biological Nanotechnology of National Health Commission, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410000, China.
Purpose: The accurate assessment of inflammatory activity of the extraocular muscles (EOMs) in thyroid associated ophthalmopathy (TAO) is crucial for formulating subsequent treatment strategies and prognostic judgments. This study aims to explore the efficacy of using [Ga]DOTATATE PET/CT to assess the inflammatory activity of EOMs in TAO patients.
Procedures: This study enrolled 22 TAO patients and 6 healthy volunteers, all of whom underwent orbital [Ga]DOTATATE PET/CT.
Sci Data
January 2025
Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
This study presents TOM500, a comprehensive multi-organ annotated orbital magnetic resonance imaging (MRI) dataset. It includes clinical data, T2-weighted MRI scans, and corresponding segmentations from 500 patients with thyroid eye disease (TED) during their initial visit. TED is a common autoimmune disorder with distinct orbital MRI features.
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