An adaptation of the definition of the basic reproduction number R (0) to time-periodic seasonal models was suggested a few years ago. However, its biological interpretation remained unclear. The present paper shows that in demography, this R (0) is the asymptotic ratio of total births in two successive generations of the family tree. In epidemiology, it is the asymptotic ratio of total infections in two successive generations of the infection tree. This result is compared with other recent work.
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http://dx.doi.org/10.1007/s00285-011-0479-4 | DOI Listing |
Some scholars have suggested that social and cultural barriers between physicians and patients might contribute to health disparities. The purpose of this review was to determine the state of evidence regarding how physician communication patterns differ by patient ethnicity. Seventy-nine studies employing a range of methodologies were identified.
View Article and Find Full Text PDFJ Gen Intern Med
January 2025
Department of Population Health Sciences, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, UT, USA.
Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may occur after infection. How often people develop ME/CFS after SARS-CoV-2 infection is unknown.
Objective: To determine the incidence and prevalence of post-COVID-19 ME/CFS among adults enrolled in the Researching COVID to Enhance Recovery (RECOVER-Adult) study.
J Cell Mol Med
January 2025
Postgraduate Training Base Alliance of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Cancer is a complex disease driven by mutations in the genes that play critical roles in cellular processes. The identification of cancer driver genes is crucial for understanding tumorigenesis, developing targeted therapies and identifying rational drug targets. Experimental identification and validation of cancer driver genes are time-consuming and costly.
View Article and Find Full Text PDFJ Exp Zool A Ecol Integr Physiol
January 2025
Programa de Pós-Graduação em Ecologia, Conservação e Manejo da Vida Silvestre, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
The Atlantic Forest broad-snouted caiman (Caiman latirostris) inhabits regions within one of the world's most ecologically diverse ecosystems, yet few studies have explored the relationship between body condition, blood biochemistry, and environmental factors in the wild. Our study investigated the effects of sex, ontogeny, habitat, and environmental variables on the body condition and blood biochemistry of free-ranging caimans from the state of Alagoas, Northeast Brazil. From 2020 to 2022, we captured 75 caimans across three sites in different seasons.
View Article and Find Full Text PDFAnthropogenic planetary heating is disrupting global alpine systems, but our ability to empirically measure and predict responses in alpine species distributions is impaired by a lack of comprehensive data and technical limitations. We conducted a comprehensive, semi-quantitative review of empirical studies on contemporary range shifts in alpine insects driven by climate heating, drawing attention to methodological issues and potential biotic and abiotic factors influencing variation in responses. We highlight case studies showing how range dynamics may affect standing genetic variation and adaptive potential, and discuss how data integration frameworks can improve forecasts.
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