Purpose Of Review: The pathogenesis and treatment paradigm for idiopathic intracranial hypertension (IIH) is controversial. The goal of this article is to review the current literature addressing a relatively new and controversial therapeutic approach for a subset of IIH patients: dural venous sinus stenting.
Recent Findings: The debate continues as to whether transverse sinus stenosis is a primary or secondary process relative to raised intracranial pressure (ICP). Transverse sinus stenosis is seen in the majority of patients with IIH and appears to play some role in the disease process. Recent case reports and case series that looked at patients treated with venous sinus stents show encouraging results in decreasing ICP and its related signs and symptoms. Venous sinus stenting could be a treatment option for many patients with IIH.
Summary: Exactly where in the treatment paradigm endovascular venous sinus stenting falls is unknown. Additional work, preferably controlled prospective studies, needs to be performed to prove its safety and efficacy. Finally, venous sinus stenting should be compared in head-to-head trials with optic nerve sheath fenestration and cerebrospinal fluid diversion surgeries to address its superiority or inferiority relative to these more traditional surgical options.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/ICU.0b013e32834bbf9f | DOI Listing |
BMJ Case Rep
January 2025
Neurosciences, Concord Repatriation General Hospital, Concord West, New South Wales, Australia
Cerebral venous sinus thrombosis is an uncommon sequela of low intracranial pressure, which may result from a lumbar puncture (LP). We describe a case of a patient in their 40s presenting with 48 hours of persistent headache following intrathecal administration of nusinersen for spinal muscular atrophy (SMA) type 3. There were no focal neurological signs or symptoms apart from baseline symmetrical proximal limb weakness attributed to SMA.
View Article and Find Full Text PDFClin Pediatr (Phila)
January 2025
Boston Medical Center, Boston, MA, USA.
J Neurointerv Surg
January 2025
Neurology, Boston Medical Center, Boston University Chobanian and Aveidisian School of Medicine, Boston, Massachusetts, USA.
Background: Transverse sinus stenosis (TSS) and sigmoid sinus wall anomalies (SSWAs) are the most common causes of pulsatile tinnitus (PT). While these conditions may co-occur, they usually require different management approaches. This study aims to evaluate whether TSS stenting alone, without targeted treatment of SSWAs, is sufficient to resolve PT in patients presenting with PT, TSS, and SSWAs.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina.
Background: Dural arteriovenous fistulas (DAVFs) are abnormal communications between dural arteries and cortical, meningeal, or dural sinus veins. They represent 10-15% of intracranial arteriovenous malformations. In rare cases, they have been associated with potentially reversible cognitive impairment and dementia.
View Article and Find Full Text PDFMed Sci Monit
January 2025
Department of Rheumatology, University Clinical Hospital No. 1 Szczecin, Szczecin, Poland.
Skeletal muscle relaxants have their place in everyday use in numerous anesthesiological procedures, such as preparing a patient for surgery, supporting mechanical ventilation, and performing effective intubation. These drugs can be divided, based on their mechanism of action, into depolarizing skeletal relaxants, such as succinylcholine, and non-depolarizing skeletal muscle relaxants. Non-depolarizing agents are further categorized, based on their structure, into steroidal (eg, rocuronium) and benzylisoquinoline (eg, atracurium) compounds.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!