Objective: To assess whether repositioning of ambulance stations in a rural county of Alabama can improve emergency medical services (EMS) response time to motor vehicle crashes (MVCs) without adversely affecting response time to non-MVC-related emergencies.
Methods: Using geographical information system software, locations of MVCs during a 9-month period in a rural county of Alabama were plotted on a map. A single ambulance station provided EMS for the entire county. Based on the number of ambulances serving the county and concentrated areas of MVCs, the county was geographically divided into two regions. A new ambulance station was assigned to each region based on high MVC concentrations and access to a major thoroughfare. The number of ambulances in-service did not change. Following establishment of both ambulance stations (redeployment), data were prospectively collected for EMS miles to scene, EMS time to scene, fatalities, and type of call (MVC vs. non-MVC) during a 9-month period (January 2006 to September 2006). The prospective data were compared with historical data (non-redeployment) from a similar time period (January 2005 to September 2005).
Results: During the redeployment period, 597 EMS calls were documented, 106 (17.8%) of which were MVCs. In all, 764 EMS calls were documented before the redeployment period, 62 (8.1%) of which were MVCs. During the redeployment period, the mean miles EMS traveled to an MVC scene was 8.6 miles versus 10.7 miles before redeployment (p=0.038). The mean time to an MVC scene was 8.0 minutes during redeployment versus 9.5 minutes before redeployment (p=0.03). During the redeployment period, the mean time to non-MVC emergencies was 8.6 minutes versus 9.2 minutes during the period before redeployment (p=0.27).
Conclusions: Utilizing geographical information system software, EMS response time to MVCs could be improved in rural areas by optimal location of ambulance stations based on geographical highest concentration of MVCs and vicinity of major thoroughfares. This can be accomplished without adversely affecting response time to non-MVC-related emergencies.
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http://dx.doi.org/10.1097/TA.0b013e318230f6f0 | DOI Listing |
Neuropsychopharmacol Rep
March 2025
Lab of Animal Behavior and Environmental Science, Graduate School of Agriculture, Meiji University, Kawasaki, Japan.
Pituitary adenylate cyclase-activating polypeptide (PACAP) affects rodents' stress-related behaviors, such as anxiety-like behavior or fear conditioning. However, previous studies have investigated the effect of intracerebroventricular, but not hippocampal, injection of this PAC1R-selective antagonist (PACAP-6-38) on anxiety-like behavior. However, it has been reported that administration of PACAP-6-38 to the dorsal hippocampus reduces the fear response in a fear conditioning test.
View Article and Find Full Text PDFBiopreserv Biobank
December 2024
Reproductive Health Research Center, Clinical Research Institute, Urmia University of Medical Science, Urmia, Iran.
Sperm cryopreservation is a useful storage technique in artificial insemination. Nanoparticles and nanovesicles such as exosomes are widely used in sperm cryopreservation procedures to alleviate cold-induced injury inflicted during sperm freezing. The objective of the present study was to examine the impact of varying concentrations of exosomes derived from seminal plasma added to a freezing extender on the quality of post-thawed bull sperm.
View Article and Find Full Text PDFRisk Manag Healthc Policy
December 2024
Psychiatry, Aalborg University Hospital, Aalborg, Denmark.
Introduction: The COVID-19 pandemic disrupted global economies, social structures, and public health systems. However, Denmark stood out as an exception, maintaining steady life expectancy during this period. This raises important questions about the factors that strengthened the Danish healthcare system and society against the pandemic's challenges.
View Article and Find Full Text PDFInt Med Case Rep J
December 2024
Department of Gerontology, Weifang No. 2 People's Hospital, Weifang, People's Republic of China.
The incidence of lung cancer is the highest among all tumors, and treatment has become an urgent problem to be solved. The Drug-eluting bead-based bronchial arterial chemoembolization (DEB-BACE) combination immunotherapy is a rare neoadjuvant therapy for lung cancer surgery, which can significantly reduce the time it takes for lung cancer patients to undergo surgery.We report a male patient, aged 59-year-old, with Stage-III b squamous cell lung cancer accompanied by hemoptysis underwent surgical resection after DEB-BACE combination immunotherapy treatment 21 days later without obvious adverse events.
View Article and Find Full Text PDFFront Oncol
December 2024
Medicine Center, Guangxi University of Science and Technology, Liuzhou, Guangxi, China.
Introduction: To assess the efficacy and safety of first-line immunotherapy-containing regimens compared with chemotherapy for advanced or metastatic urothelial carcinoma (UC).
Method: A comprehensive search was performed in four databases (Pubmed, Embase, Web of Science, and the Cochrane Library) to identify randomized controlled trials (RCTs) assessing the efficacy of first-line immunotherapy-containing regimens for advanced or metastatic UC. The search encompassed the time span from the inception of the databases to April 23, 2024.
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