Since 2004, when the World Anti-Doping Agency assumed the responsibility for establishing and maintaining the list of prohibited substances and methods in sport (i.e. the Prohibited List), cannabinoids have been prohibited in all sports during competition. The basis for this prohibition can be found in the World Anti-Doping Code, which defines the three criteria used to consider banning a substance. In this context, we discuss the potential of cannabis to enhance sports performance, the risk it poses to the athlete's health and its violation of the spirit of sport. Although these compounds are prohibited in-competition only, we explain why the pharmacokinetics of their main psychoactive compound, Δ(9)-tetrahydrocannabinol, may complicate the results management of adverse analytical findings. Passive inhalation does not appear to be a plausible explanation for a positive test. Although the prohibition of cannabinoids in sports is one of the most controversial issues in anti-doping, in this review we stress the reasons behind this prohibition, with strong emphasis on the evolving knowledge of cannabinoid pharmacology.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717337 | PMC |
| http://dx.doi.org/10.2165/11591430-000000000-00000 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Tetrahydrocannabinol (THC)-based and cannabidiol (CBD)-based products are increasing in popularity for the management of pain. Cannabis-based products may serve as a valuable alternative to traditional analgesics such as opioids for pain management among orthopedic patients. The purpose of this study was to investigate the perspective of orthopedic sports medicine patients regarding the use of THC- and CBD-based products for the management of musculoskeletal pain.
View Article and Find Full Text PDFDeveloping an HIV-specific falls risk prediction model with a novel clinical index: a systematic review and meta-analysis method.
BMC Infect Dis
December 2024
Department of Nursing Sciences, Faculty of Health Sciences & Technology, David Umahi Federal University of Health Sciences, Uburu, Ebonyi State, Nigeria.
Background: Falls are a common problem experienced by people living with HIV yet predictive models specific to this population remain underdeveloped. We aimed to identify, assess and stratify the predictive strength of various physiological, behavioral, and HIV-specific factors associated with falls among people living with HIV and inform a predictive model for fall prevention.
Methods: Systematic review and meta-analysis were conducted to explore predictors of falls in people living with HIV.
Comparison of Laboratory Confirmed Drugs in Acute Recreational Drug Toxicity Presentations to an Urban Hospital in London, UK, 2016/17 versus 2019/20.
J Med Toxicol
January 2025
Clinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, London, UK.
Introduction: Novel Psychoactive Substance (NPS) use is increasingly prevalent and is often associated with severe acute recreational drug toxicity (ARDT). 258 UK deaths were attributed to NPS use in 2021. Confirmatory testing which identifies NPS is limited by expense and timeliness.
View Article and Find Full Text PDFPerceptions and Prevalence of Anxiolytic Medication Usage for Performance Enhancement Among Musicians.
Med Probl Perform Art
December 2024
Stanford Sports Medicine, 6121 Hollis St., Ste 900, Emeryville, CA 94608, USA.
Objective: While anecdotal reports of the use of performance-enhancing medications to curb anxiety in performing artists abound, there has been no research to date assessing the prevalence of usage and attitudes towards use amongst the artists themselves. The objective of this study was to evaluate the perceptions, acquisition, and use of potentially performance-enhancing medications (benzodiazepines, beta-blockers, and cannabinoids) in the performing artist community to clarify the use of these medications to improve patient counseling and patient safety.
Design: Cross-sectional survey.
Critical Assessment of Clean-up Procedures Used for Gas Chromatography-Mass Spectrometry Analysis of Pesticide Residues in Cannabis Inflorescence.
J Sep Sci
November 2024
Department of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czech Republic.
Accurate analysis of pesticide residues in such a complex matrix as cannabis is a challenging task. The aim of this study was to find an optimal way of removing abundant matrix co-extracts from Quick, Easy, Cheap, Effective, Rugged, and Safe extract prior to its analysis by gas chromatography-tandem mass spectrometry (GC-MS/MS). Out of the seven procedures tested, clean-up with Supel QuE Verde sorbent provided the most satisfactory performance characteristics for 277 targeted pesticides, which is the highest number of these analytes ever investigated within a GC-MS-based study focused on cannabis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!