AI Article Synopsis
- The study aimed to assess the carrier rate of thalassaemia in children from 10 minority ethnic groups in three border states of Yunnan Province.
- A total of 6,562 blood samples from children under 10 years old were analyzed, revealing significant differences in carrier frequencies across regions.
- The findings indicated a high overall carrier rate of thalassaemia, particularly in Dehong (46.2%), with variations in beta and alpha thalassaemia rates among different ethnic groups, highlighting the need for targeted prevention efforts.
Article Abstract
Objective: To investigate the carrier rate of thalasaemia among the children of 10 minority ethnic groups in 3 border states (Xishuangbanna, Dehong and Nujiang) of Yunnan Province.
Methods: A total of 6562 samples of children under 10 years old were analyzed by blood cell automatic analysis and hemoglobin electrophoresis.
Results: The overall carrier frequency of thalasaemia was highest (46.2%) in Dehong, and lowest (30.6%) in Nujiang. The carrier frequency of beta-thalasaemia was the highest (40.6%) in Achang, and lowest (2.5%) in Dulong. The carrier frequency of alpha-thalasaemia was the highest (22.1%) in Dai from Xishuangbanna, followed by Dulong (19.1%).
Conclusion: Thalasaemia carrier rates were high among the children of 10 minority ethnic groups in Yunnan. There were regional differences in their incidences. The results provide a valuable basis for thalasaemia prevention in Yunnan minorities in the three border states.
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| http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2011.05.025 | DOI Listing |
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