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Zeneker's diverticulum (pharyngeal diverticulum) is a pathological sac-like protrusion of the mucous membrane at the posterior nasopharyngeal wall. Surgical operation is the principal method for the treatment of this rather rare disease. In the present paper, two cases of its successful management by means of laser-assisted endoscopic diverticulotomy are described. Both operations were made at the otorhinolaryngological clinic of Sankt-Peterburg State Medical University. Contact laser surgery was for the first time performed for the purpose.