During the last decade, several contributions to the genus Buthus Leach, 1815 (family Buthidae) and especially to the 'Buthus occitanus' species complex were proposed. These contributions led to the definition of several species, previously considered only as subspecies or varieties, and also to the description of new species. In the present study, the questionable presence of the genus Buthus in the Cyprus is rediscussed and a new species Buthus kuntisp. n. is described.
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http://dx.doi.org/10.3897/zookeys.115.1135 | DOI Listing |
J Nat Prod
March 2025
Guangdong Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics, Institute for Inheritance-Based Innovation of Chinese Medicine, Marshall Laboratory of Biomedical Engineering, School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, People's Republic of China.
Twelve guanidine derivatives (-), including seven new compounds (martensiiagms A-G, -), one new hypoxanthine derivative (martensiiagm H, ), and 15 known compounds (-) were isolated from the whole body of Karsch and identified by analysis of data. Subsequent biological evaluations revealed the anti-inflammatory activity of compound . It attenuates the neuroinflammation and oxidative stress levels prompted by lipopolysaccharide.
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February 2025
Laboratory of Pharmacology, Neurobiology, Anthropology and Environment, Department of Biology, Faculty of Sciences, Semlalia, University Cadi Ayyad, BP 2390-40080, Marrakech, Morocco.
Scorpion venom research aims to develop treatments for dangerous species and identify candidates for new drugs. The extraction of high-quality venom, which is essential, requires mastery of the extraction and maintenance of scorpions. It is in this perspective that we have undertaken this present work which aims to contribute to scientifically mastering venom yields and the factors that influence them in scorpions.
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February 2025
Laboratory of Venoms and Toxins, Pasteur Institute of Morocco, Morocco. Electronic address:
Scorpion fauna is abundant in regions with arid and semi-arid climates, exposing these areas to a risk of envenomation, especially for children. Scorpion envenomations cause thousands of deaths each year, with notable incidences in the MENA region, South America, Latin and Central America, and India. Morocco is one of the countries most affected by this phenomenon; according to statistics from the Moroccan Poison Control and Pharmacovigilance Center (CAPM), approximately 8565 scorpion stings and envenomations were recorded annually between 2016 and 2022, mainly among children.
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November 2024
Mohammed VI University of Sciences and Health, Casablanca, Morocco; Mohamed VI Center for Research & Innovation, Rabat, Morocco. Electronic address:
This study examines the effects of environmental conditions on venom production in four prevalent scorpion species in Morocco: Androctonus amoreuxi, Androctonus mauretanicus, Buthus mardochei, and Scorpio maurus. The research focuses on how climatic factors such as temperature, humidity, and diet-specifically mealworm consumption-affect physical parameters including size and weight, and ultimately venom yield. We conducted a comprehensive investigation involving the capture, acclimatization, and systematic venom extraction from 480 scorpions.
View Article and Find Full Text PDFWilderness Environ Med
September 2024
Polyvalent Team of Research and Development (EPVRD), Department of Biology and Geology, Polydisciplinary Faculty, Sultan Moulay Slimane University, Beni Mellal, Morocco.
Introduction: species, including , are classified as one of the most dangerous scorpion genera in Morocco, implicated in several cases of human death. Our objective is to characterize, for the first time, the toxicity and histopathologic and biochemical impacts of venom.
Methods: We investigated the experimental pathophysiology of venom by examining histologic changes in vital organs (heart, kidneys, liver, and lungs) and assessing biochemical enzymatic markers (alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, creatine phosphokinase, urea, and creatinine) in mice injected subcutaneously with 2 doses of 400 and 450 mg·kg.
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