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Superscan Pattern on Bone Scintigraphy: A Comprehensive Review.
Diagnostics (Basel)
October 2024
Department of Nuclear Medicine, The Hospital for Sick Children, University of Toronto, Toronto, ON M4N 3M5, Canada.
Article Synopsis
- The superscan pattern is a key finding on bone scans, indicating various metabolic and cancer-related diseases, characterized by widespread radiotracer uptake in the skeleton.
- This review analyzes existing literature to clarify the pathophysiology, clinical importance, and diagnostic challenges related to the superscan pattern in bone scintigraphy.
- Accurate diagnosis is essential, as misinterpretation can complicate patient management, highlighting the need for careful differential diagnoses when encountering this pattern.
High-Grade Hepatic Spindle Cell Carcinoma as a Cause of Diffuse Right Hepatic Lobe Hypermetabolism Identified With 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) Imaging.
Cureus
September 2024
Nuclear Medicine and Positron Emission Tomography/Computed Tomography (PET/CT), King Hussein Cancer Center (KHCC), Amman, JOR.
Article Synopsis
- A 70-year-old man presented with severe symptoms including hiccups, belching, appetite loss, and significant weight loss over three months, prompting further investigation.
- F-FDG PET/CT imaging revealed a tumor in the right liver lobe exhibiting abnormal metabolic activity, indicating an aggressive form of cancer.
- A biopsy confirmed the diagnosis of high-grade spindle cell sarcoma, but the patient passed away shortly after, limiting treatment options.
Complimentary Role of [18F]FDG and [18F]NaF-PET/CT in Evaluating Synchronous Thyroid Carcinoma and Parathyroid Adenoma with Brown Tumors.
World J Nucl Med
September 2024
Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Hospital, Mumbai, Maharashtra, India.
We herein present a patient initially suspected of multiple lytic skeletal metastasis of unknown primary on anatomical imaging. Metabolic imaging by [18F]-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) detected focal [18F]FDG uptake in the right thyroid nodule, mild [18F]FDG uptake in soft tissue lesion in the left inferior parathyroid region, and multiple nonavid osteolytic skeletal lesions. Fine-needle aspiration cytology of the right thyroid nodule showed papillary thyroid carcinoma (PTC).
View Article and Find Full Text PDFSuperscan on Ga PSMA PET/CT in patients with metastatic prostate carcinoma: A case series.
Arch Clin Cases
December 2023
Instituto Nacional de Cancerologia, Bogota, Colombia.
Prostate cancer is the second most common malignancy in men worldwide, with a good prognosis when is detected and treated in early stages, but, when it presents progression to castration-resistant metastatic prostate cancer, most of the cases will have bone metastasis, decreasing the quality of life and life expectancy. For the evaluation of the disease in the routinary clinical practice, Ga-PSMA PET/CT, among others is a valuable tool for the evaluation of the disease extension. Ga-PSMA PET/CT detects the presence of PSMA receptor in the tumoral tissue, but also has physiologic uptake in certain organs, such as liver, spleen, intestine, kidneys, lacrimal and salivary glands.
View Article and Find Full Text PDFGradual normalization of superscan in prostate cancer: A case report and literature review.
Radiol Case Rep
December 2023
Department of Radiology, University of Texas Medical Branch, Galveston, TX, 77555, USA.
This report presents the imaging findings in a patient with advanced prostate cancer and bone metastases. A superscan pattern on the initial whole-body bone scan suggested extensive disease. The patient responded well to definitive treatment, exhibiting clinical improvement based on decreased PSA levels and CT findings in 6-month follow-up.
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