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Article Synopsis
  • Shivering is a common issue during spinal anesthesia, and this review investigates the effectiveness of ketamine in preventing it, using major medical databases for research.
  • Out of studies comparing ketamine to saline and tramadol, ketamine showed mixed results; some studies found it more effective while others suggested similar or better outcomes for other drugs like dexmedetomidine and meperidine.
  • Ketamine appears to be a safe option for reducing shivering, especially with dosages of 0.2-0.5 mg/kg, but other medications may work just as well or better, and factors like patient type and doctor experience should guide treatment choices.
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Sedation techniques in interventional flexible bronchoscopy and endobronchial ultrasound-guided transbronchial-needle aspiration (EBUS-TBNA) are inconsistent and the evidence for required general anesthesia under full anesthesiologic involvement is scarce. Moreover, we faced the challenge of providing bronchoscopic care with limited personnel. Hence, we retrospectively identified 513 patients that underwent flexible interventional bronchoscopy and/or EBUS-TBNA out of our institution between January 2020 and August 2022 to evaluate our deep analgosedation approach based on pethidine/meperidine bolus plus continuous flow adjusted propofol, the bronchoscopist-directed continuous flow propofol based analgosedation (BDcfP) in a two-personnel setting.

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Purpose: Safe and effective analgesia sub partu is one of the central issues in optimizing vaginal delivery birth experiences. Meptazinol is a common opiate approved for treating labor pain in the first stage of labor. According to the manufacturer, manual meptazinol can be applied intramuscularly or intravenously.

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Pharmacologic and nonpharmacologic options for pain relief during labor: an expert review.

Am J Obstet Gynecol

May 2023

Department of Obstetrics and Gynecology, Emek Medical Center, Afula, Israel; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department of Obstetrics and Gynecology, Holy Family Hospital, Nazareth, Israel. Electronic address:

Labor pain is among the most severe types of physical pain that women may experience during their lifetime. Thus, pain relief is an essential part of medical care during childbirth. Epidural analgesia is considered to be the most efficient method of pain relief during labor.

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Background/aim: To survey the safety and efficacy of percutaneous cryoablation for renal tumors under local anesthesia and pain control by using the -40°C lethal isotherm of the ice ball to cover the tumor margin as well as the coaxial cryoablation technique.

Patients And Methods: All procedures were performed between February 2014 and November 2021 with computed tomography (CT) guidance. All tumors were ablated by following the aforementioned plan, according to which tumor margins were covered by the -40°C lethal isotherm.

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