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Reversal of Digital Ischemia with Phentolamine After Accidental Epinephrine Injection.
Am J Case Rep
September 2020
Department of Emergency Medicine, King Abdullah Bin Abdulaziz University Hospital, Riyadh, Saudi Arabia.
BACKGROUND Accidental finger-stick injuries have been reported with epinephrine autoinjectors, such as EpiPen and EpiPen Jr, and can result in necrosis and digital ischemia. However, long-term adverse effects are very rare. The treatment for accidental finger-stick injuries is controversial and includes intra-arterial injections of vasodilating agents, topical vasodilators, and supportive management as needed.
View Article and Find Full Text PDFDown-regulation of miR-140-3p can alleviate neonatal repetitive pain in rats via inhibiting TGF-β3.
Biochem Biophys Res Commun
August 2019
The Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and Embryology, Nanjing Medical University, Nanjing, People's Republic of China. Electronic address:
MicroRNAs (miRNAs) have been shown to be involved in the pathophysiological processes of pain. At present, the roles and mechanisms of miRNAs in neonatal repetitive pain are largely unknown. In our research, the expression of miR-140-3p was increased in premature infants who received repetitive painful stimuli since admission, and in rat pups after repetitive needlestick stimulation.
View Article and Find Full Text PDFThe impact of metallothionein-II on microglial response to tumor necrosis factor-alpha (TNFα) and downstream effects on neuronal regeneration.
J Neuroinflammation
February 2018
Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Macquarie University, 2 Technology Place, Sydney, NSW, 2109, Australia.
Background: The extracellular environment plays an important role in supporting the regeneration of axons after injury. Metallothionein-II (MTII) is a metal-binding protein known for its neuroprotective effect by directly stimulating the growth of axons after injury. Previous studies have shown that MTII also modulates the response of astrocytes and microglia after injury.
View Article and Find Full Text PDFAccidents at work in the health care - legal aspects in Poland.
Pol Merkur Lekarski
January 2016
Chair and Department of Pedodontics, Medical University of Lublin, Poland.
An accident at work is a sudden event caused by external circumstances that occurred in relation to work. Referring to the current legislation, the Supreme Court judgments and the opinions contained in publications, the authors discuss the legal aspects of selected accidents: needle stick injuries, cuts with other sharp tools, heart attacks and strokes among health professionals and social workers in Poland. It has been stressed that defining rigid criteria that allow for stating unequivocal work - accidents relationships would be difficult or even impossible.
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