The cerebellar cortex contains two astrocyte types: the Bergmann glia of the molecular layer and the velate protoplasmic astrocytes of the granule cell layer. In vivo, these cell types generate both subcellular calcium transients and trans-glial calcium waves. It is possible to perform in vivo calcium imaging in cerebellar astrocytes. One method involves injection of a replication-incompetent recombinant adenovirus for gene transfer of a fluorescent calcium indicator protein. A second method uses multicell bolus loading (MCBL) in the molecular layer of the cerebellum with synthetic calcium indicators. This protocol presents a cerebellar craniotomy procedure which can be used to prepare a virus-injected animal for in vivo imaging. It can also be used to prepare an animal for MCBL.
Case Summary: A 13-year-old castrated male American Shorthair cat was referred for evaluation following a 3-week history of poor balance and decreased activity. The MRI findings revealed a well-defined left caudal cerebellar mass with a diameter of 1.2 cm, consistent with a meningioma.
We report a case of a 42-year-old female who had non-cardiogenic pulmonary edema following a setting position craniotomy to remove a left cerebellar pontine angle mass. During the operation, the patient experienced a sudden drop in her end-tidal CO2 levels, which needed an immediate intervention. After ruling out other potential causes, we determined that air venous embolism was the cause of this unexpected and serious complication.
Purpose: Ophthalmic artery (OphA) embryogenesis is a complex process with various origins. We describe herein a case in which the OphA stemmed from the persistent primitive trigeminal artery (PPTA), which has never been reported.
Methods: A man in his 70s was admitted to our hospital following the sudden onset of altered consciousness.
Background: Cerebellar infarction can lead to severe morbidity and mortality. Current surgical options include decompressive craniectomy (DC) and endoscopic minimally invasive evacuation of necrotic tissue (MEN), but no randomized studies compare their outcomes.This study compares outcomes between DC and MEN in patients with cerebellar infarct using the Glasgow Coma Scale (GCS) and Scale for the Assessment and Rating of Ataxia (SARA) scores.
Gliomas and meningiomas are two common primary brain tumors, but occurring simultaneously in the same patient is a rare entity. The authors would like to report a case of coexistence of a superior parietal lobule diffuse glioma, IDH-wild type, histologically CNS WHO grade 3 and a left posterior fossa transitional meningioma, WHO grade 1; both the tumors were successfully removed in one-stage operation. A 68-year-old female having hypertension, who presented to us with the chief complaints of involuntary shaking of her left lower limb associated with her left upper limb tingle, dizziness, and neck soreness.
