This study investigated the developmental variability of lip and tongue movement in 48 children and adults. Motion of the tongue-tip, tongue-body and lower lip was recorded using electromagnetic articulography during productions of sentences containing /t/, /s/, /l/, /k/ and /p/. Four groups of speakers participated in the study: (1) aged 6-7 years; (2) 8-11 years; (3) 12-17 years; and (4) adults. The variation in distance, duration, speed, acceleration and deceleration of the articulators during single open-close speech movements was analysed, and the stability of multiple movement sequences was examined using the spatiotemporal index. The experimental findings revealed a gradual developmental progression from 6 years to adulthood. At adolescence, speakers continued to exhibit significantly more variable speech motor output compared to adult speakers. The observed developmental pattern suggests that attenuated, but important, changes in the speech motor system occurs from mid-childhood, through adolescence, to adulthood.
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http://dx.doi.org/10.3109/02699206.2011.604459 | DOI Listing |
Front Oncol
January 2025
Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Accurate preoperative mapping is crucial for maximizing tumor removal while minimizing damage to critical brain functions during brain tumor surgery. Navigated transcranial magnetic stimulation (nTMS), magnetoencephalography (MEG), and functional magnetic resonance imaging (fMRI) are established methods for assessing motor and language function. Following PRISMA guidelines, this systematic review analyzes the reliability, clinical utility, and accessibility of these techniques.
View Article and Find Full Text PDFElife
January 2025
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University & IDG/McGovern Institute for Brain Research, Beijing, China.
Speech comprehension involves the dynamic interplay of multiple cognitive processes, from basic sound perception, to linguistic encoding, and finally to complex semantic-conceptual interpretations. How the brain handles the diverse streams of information processing remains poorly understood. Applying Hidden Markov Modeling to fMRI data obtained during spoken narrative comprehension, we reveal that the whole brain networks predominantly oscillate within a tripartite latent state space.
View Article and Find Full Text PDFMol Genet Genomic Med
January 2025
Department of Medical Genetics, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: X-linked intellectual disability (XLID) is a genetically heterogeneous disorder that results in cognitive impairment and developmental delays. Mutations in the KDM5C gene have been identified as a causative factor in XLID. This study aimed to identify novel variants associated with XLID and to investigate the clinical and genetic characteristics of XLID patients with mutations in the KDM5C gene.
View Article and Find Full Text PDFMamm Genome
January 2025
The Gene Therapy Research Institute, CTNNB1 Foundation, Ljubljana, 1000, Slovenia.
CTNNB1 syndrome is a rare neurodevelopmental disorder, affecting children worldwide with a prevalence of 2.6-3.2 per 100,000 births and often misdiagnosed as cerebral palsy.
View Article and Find Full Text PDFAnn Intern Med
January 2025
959 Medical Operations Squadron, U.S. Air Force, Department of Neurology, Brooke Army Medical Center, San Antonio, Texas (T.K.).
Description: In July 2024, the U.S. Department of Veterans Affairs (VA) and U.
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