AI Article Synopsis

  • This study evaluated how effective motor responses are in detecting contact between catheters and nerves using ultrasound as a reference.
  • In a trial involving 25 patients, stimulating catheters were used, and muscle contractions were measured as the current increased; a 0.5 mA threshold was established.
  • The findings showed that only 64% of patients responded at this current level, indicating that a lack of muscle response does not confirm there is no contact between the catheter and nerve.

Article Abstract

Background: We determined the sensitivity of motor responses evoked by stimulating catheters in determining catheter-nerve contact using ultrasonography as reference.

Methods: Femoral nerves were contacted using stimulating catheters under ultrasonography scanning in 25 patients. The output current was increased from its minimum until quadriceps muscle contraction occurred. The sensitivity of the motor response in determining catheter-nerve contact was calculated using 0.5 mA as current threshold.

Results: The current required for catheter stimulation to evoke a motor response ranged between 0.18 and 2.0 mA. Muscle contraction in response to 0.5 mA occurred in 16 of 25 subjects. The sensitivity of motor response for nerve stimulation was 64% (95% confidence interval: 0.43, 0.82).

Conclusions: The absence of muscle responses at a stimulating current≤0.5 mA does not necessarily indicate the absence of catheter-nerve contact.

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0b013e31822c9887DOI Listing

Publication Analysis

Top Keywords

sensitivity motor
16
catheter-nerve contact
16
stimulating catheters
12
motor response
12
motor responses
8
determining catheter-nerve
8
muscle contraction
8
motor
5
report sensitivity
4
responses detecting
4

Similar Publications

When rendering the visual scene for near-eye head-mounted displays, accurate knowledge of the geometry of the displays, scene objects, and eyes is required for the correct generation of the binocular images. Despite possible design and calibration efforts, these quantities are subject to positional and measurement errors, resulting in some misalignment of the images projected to each eye. Previous research investigated the effects in virtual reality (VR) setups that triggered such symptoms as eye strain and nausea.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.

Background: Dopamine transporter (I-FP-CIT) single-photon emission tomography (SPECT) and I-meta-iodobenzylguanidine (I-MIBG) image play roles as indicative biomarkers in diagnosing patients with dementia with Lewy bodies (DLB). Brain- and body-first subtypes of DLB were hypothesized implying that subset of DLB may have normal I-FP-CIT or I-MIBG results, respectively. The purpose of this study was to explore the diagnostic sensitivity of two combination imaging modalities (I-FP-CIT SPECT and I-MIBG image) in patients with DLB and examine the clinical difference between brain- and body-first subtype.

View Article and Find Full Text PDF

Background: Detection of presymptomatic individuals or those with subtle cognitive changes in midlife may prevent or slow the course of Alzheimer's Disease by identifying candidates for disease-modifying treatments. Utilizing newer delivery approaches involving digital measures shows promise for cognitive phenotyping, early detection, ease of administration, and scoring, particularly in low-resource settings. However, the feasibility of these approaches, along with their association with demographics and their effectiveness in detecting fine-grained aspects of cognitive performance in low-resource settings, remains unclear.

View Article and Find Full Text PDF

Background: TDP-43 (TAR DNA-binding protein 43) is one of the most frequently observed co-pathologies in Alzheimer's disease (AD). Recognizing the diversity of pathological features in individuals with AD, including the presence of TDP-43, may lead to more personalized and effective treatment approaches. We investigate ante-mortem cortical microstructural changes in MRI with subsequent autopsy confirmation of Alzheimer's disease neuropathological changes (ADNC) with and without TDP-43 comorbidity.

View Article and Find Full Text PDF

Background: Identification of useful fluid biomarkers is expected to advance frontotemporal dementia spectrum disorders (FTD) care and therapeutic development. The clinical utility of emerging plasma Amyloid, Tau, and Neurodegeneration (ATN) biomarkers in FTD remains unexplored. This study analyzed ATN patterns by sporadic FTD phenotype, based on amyloid beta (Aβ), amyloid beta (Aβ), phospho-tau217 (p-tau217), and neurofilament (NfL) plasma concentrations.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!