AI Article Synopsis
- Six compounds were isolated from the aerial parts of the Argentinean plant Hymenoxys robusta, using advanced spectroscopic techniques to determine their structures.
- The isolated compounds include two inositol derivatives and four 3,4-seco-pseudoguaianolides, one of which is called vermeerin.
- Vermeerin demonstrated antimicrobial activity specifically against Staphylococcus aureus and was non-toxic to human-derived macrophages in bioactivity assays.
Article Abstract
Six compounds from the aerial parts of the Argentinean plant Hymenoxys robusta (Rusby) Parker were isolated and their structures elucidated using extensive spectroscopic analyses. These compounds comprise two inositol derivatives and four 3,4-seco-pseudoguaianolides, including vermeerin. Bioactivity assays of these compounds against bacterial and fungal pathogens showed that only vermeerin possessed antimicrobial activity specific against Staphylococcus aureus, and showed no toxicity when exposed to human-derived macrophages.
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| http://dx.doi.org/10.1016/j.phytochem.2011.09.001 | DOI Listing |
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