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Global Inequalities in the Burden of Gallbladder and Biliary Tract Cancer From 1990 to 2021: Findings From the Global Burden of Disease Study 2021.
J Gastroenterol Hepatol
January 2025
Department of Hepatobiliary and Pancreatic Surgery, Fuyang People's Hospital, Fuyang, China.
Observational Study of Best Supportive Care With or Without Oral Capecitabine in Patients With Metastatic Gallbladder Carcinoma at a Tertiary Center in India.
JCO Glob Oncol
January 2025
Department of Radiotherapy, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Purpose: To compare overall survival (OS), toxicity, and quality of life (QOL) in patients with metastatic gallbladder cancer receiving oral capecitabine (X) with best supportive care (BSC) and BSC alone.
Materials And Methods: Patients with metastatic gallbladder cancer and Karnofsky Performance Status (KPS) ≥70 were accrued and assigned to either arm A or B. Assignment to these two arms was based on physician/patient discretion.
Gallbladder-derived retinoic acid signalling drives reconstruction of the damaged intrahepatic biliary ducts.
Nat Cell Biol
January 2025
State Key laboratory of Genetic Engineering, School of Life Sciences, Liver Cancer Institute of Zhongshan Hospital, Fudan University, Shanghai, China.
Severe damage to the intrahepatic biliary duct (IHBD) network occurs in multiple human advanced cholangiopathies, such as primary sclerosing cholangitis, biliary atresia and end-stage primary biliary cholangitis. Whether and how a severely damaged IHBD network could reconstruct has remained unclear. Here we show that, although the gallbladder is not directly connected to the IHBD, there is a common hepatic duct (CHD) in between, and severe damage to the IHBD network induces migration of gallbladder smooth muscle cells (SMCs) to coat the CHD in mouse and zebrafish models.
View Article and Find Full Text PDFPTCD and choledochoscopy for recurrent choledocholithiasis after multiple abdominal surgeries: a case report.
Front Med (Lausanne)
December 2024
Department of General Surgery, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.
Background: Special attention should be given to intra-abdominal adhesions in patients with a history of open cholecystectomy for gallstones or abdominal surgery. Choosing the appropriate surgical approach to remove the stones is crucial.
Patient Summary: A 68-year-old male was admitted due to sudden onset of upper abdominal pain lasting more than 6 h.
Spatial Association of Surface Water Quality and Cancer in the Huaihe River Basin.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
December 2024
Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Department of Epidemiology and Biostatistics, School of Basic Medicine, Peking Union Medical College,Beijing 100005,China.
Objective To reveal the spatial distribution patterns of key pollutants in the Huaihe River Basin and quantify the risks and burdens of non-gastrointestinal cancers by the grade of pollution,providing targets and data support for enhanced management of water pollution in the Huaihe River Basin. Methods Surface water quality data of the Huaihe River Basin were obtained from the National Surface Water Environmental Quality Monitoring Network(2021).Incidence data of seven cancers were extracted from the 2019 Annual Report of the China Cancer Registry.
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