Synthesis and biological evaluation of novel (thio)urea derivatives as potential antitumor agents.

Arch Pharm (Weinheim)

Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, P. R. China.

Published: November 2011

A series of novel (thio)ureas containing the pyrimidinyl group was designed and synthesized. Their in-vitro antitumor activity against different human tumor cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further studies on structure modification.

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Source
http://dx.doi.org/10.1002/ardp.201000267DOI Listing

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