The intensity of antibiotic usage in the university hospital and the investigation of an inappropriate use of antibiotics.

Aims: In the present study, we intended to investigate the intensity of antibiotic administration in our hospital and the ratio of an inappropriate antibiotic usage.

Material And Method: Related data was collected during 3 consecutive days between 1-3 July 2009 at the Mustafa Kemal University, Faculty of Medicine Hospital. The antimicrobial usage was calculated as defined daily doses (DDDs) per 100 bed-days (BD) according to 2009 ATC-DDD index.

Results: Antibiotics were administered to 74 patients (61.5%) out of 121 who were hospitalized in our hospital. Antibiotic usage in the internal clinics was intended for therapeutical reasons in 18 patients (94.7%) and for prophylactic reasons in 35 patients (77.8%) in the surgical clinics. The use of antibiotics in 44 patients (59.7%) out of 74 was appropriate. However, an inappropriate antibiotic use was detected in 30 patients (40.5%). The inappropriate antibiotics were administered to 21 patients (70%) who were hospitalized in the surgical clinics. A three days total antimicrobial consumption index value in the hospital was 81,19 DDD/100 BD, while this value was found 25,45 DDD/100 BD for the internal clinics and 38,39 DDD/100 BD for the surgical clinics. A positive correlation was observed among the inappropriate antibiotic usage and the antibiotic consumption (p<0.001).

Discussion: Consequently, the ratio of an inappropriate antibiotic usage in our hospital is high and parallel to this, the antibiotic consumption ratio is excessive. It is necessary to share microbiological data and provide an adequate education to reduce the antibiotic consumption and enable a better and rational antibiotic consumption (Tab. 2, Fig. 2, Ref. 22).