The following discussion of the esophagogastric junctions includes commentaries on the three component structures of the sphincteric segment between the stomach and the esophagus; the pressure contributions from the three sphincteric components in normal subjects and in gastroesophageal reflux (GERD) patients; the mechanism of action of endoscopic plication to determine the underlying pathophysiology of GERD; and in vitro muscle strip studies of defects within the gastroesophageal sphincteric segment potentially leading to GERD.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276069 | PMC |
| http://dx.doi.org/10.1111/j.1749-6632.2011.06073.x | DOI Listing |
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