AI Article Synopsis
- This unit explains how molecular-targeted agents, especially those impacting tumor blood vessels, influence radiation therapy.
- It discusses key factors that can affect the results of experiments with tumor models using radiation and drug combinations.
- Additionally, it outlines specific protocols for applying radiation therapy, both on its own and in combination with chemotherapy or molecular-targeted agents.
Article Abstract
This unit (1) provides background into understanding how agents that target specific molecules or receptors (molecular-targeted agents), in particular, agents affecting the tumor vasculature (perivasculature network in tumors), interact with and modify radiation therapy; (2) details factors affecting interpretation of results in murine tumor model experiments utilizing radiation therapy and drug combinations; and (3) provides specific protocols for the application of radiation therapy, both alone and in combination with chemotherapy and/or molecular-targeted agents.
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| http://dx.doi.org/10.1002/0471141755.ph1407s38 | DOI Listing |
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