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Imaging Fibroblast Activation Protein: Direct Visualization of Matrix Proteolytic Activity in Patients Post Myocardial Infarction.
J Am Coll Cardiol
December 2024
Section of Cardiovascular Medicine, Department of Medicine, Yale University, School of Medicine, New Haven, Connecticut, USA; Department of Radiology and Biomedical Imaging, Yale University, School of Medicine, New Haven, Connecticut, USA; Department of Biomedical Engineering, Yale University, New Haven, Connecticut, USA. Electronic address:
Myocardial Fibroblast Activation After Acute Myocardial Infarction: A Positron Emission Tomography and Magnetic Resonance Study.
J Am Coll Cardiol
November 2024
British Heart Foundation Centre of Research Excellence, the University of Edinburgh, Edinburgh, Scotland, United Kingdom.
Background: Myocardial fibrosis is a key healing response after myocardial infarction driven by activated fibroblasts. Gallium-68-labeled fibroblast activation protein inhibitor ([Ga]-FAPI) is a novel positron-emitting radiotracer that binds activated fibroblasts.
Objectives: The aim of this study was to investigate the intensity, distribution, and time-course of fibroblast activation after acute myocardial infarction.
Higher Aircraft Noise Exposure Is Linked to Worse Heart Structure and Function by Cardiovascular MRI.
J Am Coll Cardiol
December 2024
UCL MRC Unit for Lifelong Health and Ageing, University College London, London, United Kingdom; UCL Institute of Cardiovascular Science, University College London, London, United Kingdom; Centre for Inherited Heart Muscle Conditions, Cardiology Department, Royal Free Hospital, London, United Kingdom. Electronic address:
Background: Aircraft noise is a growing concern for communities living near airports.
Objectives: This study aimed to explore the impact of aircraft noise on heart structure and function.
Methods: Nighttime aircraft noise levels (L) and weighted 24-hour day-evening-night aircraft noise levels (L) were provided by the UK Civil Aviation Authority for 2011.
A More Accurate Diagnosis of Hypertrophic Cardiomyopathy: Simplifying the Complex Through Use of AI Technologies.
J Am Coll Cardiol
December 2024
Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
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